Polyrotaxanes

 
National Institutes of Health

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2015
2015
Niemann-Pick type C (NPC) disease is characterized by the lysosomal accumulation of cholesterols and impaired autophagic flux due… (More)
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2014
2014
Niemann-Pick type C (NPC) disease is an autosomal recessive lysosomal trafficking disorder, in which the cholesterols are… (More)
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2013
2013
To achieve successful delivery of siRNA therapeutics, cytocleavable cationic polyrotaxanes (PRXs) composed of N,N… (More)
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2012
2012
Cationic polyrotaxanes, obtained by temperature activated threading of cationic cyclodextrin derivatives onto water-soluble… (More)
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2012
2012
Safe and effective gene delivery is essential to the success of gene therapy. We synthesized and characterized a novel nonviral… (More)
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2011
2011
Functionalized polyrotaxanes are utilized to investigate the relation to multivalent interactions between the mannose moiety and… (More)
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2009
2009
The mobility of cyclodextrins (CDs) threaded onto a linear polymeric chain and the dethreading of the CDs from the chain are the… (More)
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2003
2003
A series of conjugated polyrotaxane insulated molecular wires are synthesised by aqueous Suzuki polymerisation, using hydrophobic… (More)
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2002
2002
Control of intermolecular interactions is crucial to the exploitation of molecular semiconductors for both organic electronics… (More)
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1998
1998
Cellular response to our designed biodegradable polyrotaxanes was evaluated in terms of physicochemical interaction with plasma… (More)
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