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Polyamine Analogue

A compound that mimics the naturally occurring polyamines but is modified in such a way that its function differs from that of the natural polyamines… 
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Selective regulation of polyamine metabolism with methylated polyamine analogues
Polyamine metabolism is intimately linked to the physiological state of the cell. Low polyamines levels promote growth cessation… 
2011
2011
Influence of polyamine analogue DENSPM on cell growth of human SNB19 glioblastoma cells
Objective To investigate the influence of polyamine analogue DENSPM(N1,N11- diethylnorspermine) on cell growth of human SNB19… 
2009
2009
Effect of polyamine analogue BENS on proliferation of melanoma B16-F1 cells
Objective:To study the effects of polyamine analogue BENS [N1, N11-bis(ethyl) norspermine] on proliferation and apoptosis of… 
Review
2009
Review
2009
Progress of polyamine analogue and its antineoplastic mechanism
Polyamine analogue is a new type of antitumor agents. The antitumor effects of polyamine analogue were exerted by interfering… 
2006
2006
Cancer Efficacy and Enhanced Radiosensitivity of Human Prostate 1 , 12-Diaziridinyl-4 , 9-diazadodecane , Results in Therapeutic Tumor-targeted Apoptosis by a Novel Spermine Analogue
Interference with polyamine transport and biosynthesis has emerged as an important anticancer strategy involving polyamine… 
2006
2006
TITLE: Antineoplastic Efficacy of Novel Polyamine Analogues in Human Breast Cancer. PRINCIPAL INVESTIGATOR:
Intracellular polyamines are absolutely required for cell proliferation and many tumors have abnormal requirements for polyamines… 
2005
2005
Antineoplastic Efficacy of Novel Polyamine Analogues in Human Breast Cancer
Abstract : The important role of polyamine in regulation of cell growth has led to the development of a number of polyamine… 
2004
2004
A New Synthesis of α-Methylspermidine
A five-step synthesis of α-methylspermidine (1,8-diamino-5-azanonane), the first polyamine analogue preventing pathological… 
2004
2004
[A new synthesis of alpha-methylspermidine].
A five-step synthesis of alpha-methylspermidine (1,8-diamino-5-azanonane), the first polyamine analogue preventing pathological… 
1983
1983
A polyamine-sensitive mutant of Aspergillus nidulans.
A mutation designated spsA1 has been induced in the putrescine (puA2) auxotroph of Aspergillus nidulans which enables this mutant…