Polyadenylation

Known as: Polyadenylations, RNA Polyadenylation 
The addition of a tail of polyadenylic acid (POLY A) to the 3' end of mRNA (RNA, MESSENGER). Polyadenylation involves recognizing the processing site… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
We developed PolyA-seq, a strand-specific and quantitative method for high-throughput sequencing of 3' ends of polyadenylated… (More)
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Highly Cited
2010
Highly Cited
2010
In eukaryotes, U1 small nuclear ribonucleoprotein (snRNP) forms spliceosomes in equal stoichiometry with U2, U4, U5 and U6 snRNPs… (More)
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Highly Cited
2009
Highly Cited
2009
In cancer cells, genetic alterations can activate proto-oncogenes, thereby contributing to tumorigenesis. However, the protein… (More)
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Highly Cited
2009
Highly Cited
2009
Core RNA-processing reactions in eukaryotic cells occur cotranscriptionally in a chromatin context, but the relationship between… (More)
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Highly Cited
2009
Highly Cited
2009
The 3' untranslated regions (3' UTRs) of mRNAs contain cis-acting elements for posttranscriptional regulation of gene expression… (More)
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Highly Cited
2008
Highly Cited
2008
Through alternative processing of pre-messenger RNAs, individual mammalian genes often produce multiple mRNA and protein isoforms… (More)
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Highly Cited
2005
Highly Cited
2005
The exosome complex of 3'-5' exonucleases participates in RNA maturation and quality control and can rapidly degrade RNA-protein… (More)
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Highly Cited
2005
Highly Cited
2005
Alternative polyadenylation is one of the mechanisms in human cells that give rise to a variety of transcripts from a single gene… (More)
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Highly Cited
2000
Highly Cited
2000
The formation of mature mRNAs in vertebrates involves the cleavage and polyadenylation of the pre-mRNA, 10-30 nt downstream of an… (More)
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Highly Cited
1981
Highly Cited
1981
The complete sequence of the 16,569-base pair human mitochondrial genome is presented. The genes for the 12S and 16S rRNAs, 22… (More)
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