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Poly-alendronate Dextran-Guanidine Conjugate

Known as: Dextran/Alendronate/Guanidine-containing Polybisphosphonate, ODX 
A polybisphosphonate dextran-guanidine conjugate with potential anti-resorptive and antineoplastic activities. Alendronic acid and aminoguanidine… 
National Institutes of Health

Related topics

Related topics

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NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Impact of 21‐Gene Expression Assay on Staging Estrogen Receptor–Positive HER2‐Negative Breast Cancer
2018
2018
Multigene Signature Panels and Breast Cancer Therapy: Patterns of Use and Impact on Clinical Decision Making.
2018
2018
Prognostic Value of the Detection of Lymphovascular Invasion in Hormone Receptor-Positive Early Breast Cancer in the Era of Molecular Profiling
Background: Lymphovascular invasion (LVI) is considered a negative prognostic factor in early breast cancer, but its role in… 
Review
2016
Review
2016
Influence of a 21-Gene Recurrence Score Assay on Chemotherapy Delivery in Breast Cancer.
2014
2014
Population-based evaluation of 21-gene assay in treatment decision making for early breast cancer in Ontario.
583 Background: The OncotypeDX 21-gene assay (ODX) is used to aid in decision-making for chemotherapy (CT) in patients with… 
2011
2011
P1-10-04: Cost-Utility of the 21-Gene Breast Cancer Assay (Oncotype DX®) in the Irish Healthcare Setting.
Objective: The Oncotype DX® Breast Cancer Test is a validated 21-gene assay that predicts the likelihood of benefit from adjuvant… 
2011
2011
Treatment of bone metastasis in prostate cancer: efficacy of a novel polybisphosphonate.
AIM To investigate the in vivo efficacy of a novel polybisphosphonate (ODX) in the treatment of bone metastasis from prostate… 
Review
2007
Review
2007
How well do standard prognostic criteria predict oncotype DX (ODX) scores
576 Background: In node-negative, ER + breast cancer, gene expression profiling can identify level of risk and, in the case of… 
2000
2000
Effect of Orchidectomy on the Age-Related Modulation of IL-1β and IL-1 Receptors following Lipopolysaccharide Treatment in the Mouse
Objective: To compare the effect of orchidectomy (ODX) in 7- and 24-week-old C57BL/6 mice on the age-related responses of the… 
1995
1995
Repeated endotoxin treatment decreases immune and hypothalamo-pituitary-adrenal axis responses: effects of orchidectomy and testosterone therapy.
It is known that in vivo administration of bacterial endotoxin activates immune cells to release cytokines, these substances in… 
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