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Pleiotropic Gene

Known as: Gene, Pleiotropic, Genes, Pleiotropic, Pleiotropic Genes 
A single gene that influences several distinct and seemly unrelated phenotypic outcomes.
National Institutes of Health

Papers overview

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2019
2019
BACKGROUND Genome-wide association studies have been extensively applied in identifying SNP associated with major psychiatric… Expand
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2019
2019
BACKGROUND Although genome-wide association studies (GWAS) have been extensively applied in identifying SNP associated with… Expand
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2018
2018
Previous studies have demonstrated the genetic correlations between type 2 diabetes, obesity and dyslipidemia, and indicated that… Expand
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2016
2016
Two complementary methods, namely Multi-Trait Meta-Analysis and Versatile Gene-Based Test for Genome-wide Association Studies… Expand
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2012
2012
Type 1 diabetes mellitus (T1DM), celiac disease (CD) and autoimmune thyroid disease (ATD) are autoimmune conditions relatively… Expand
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2011
2011
The risk of type 2 diabetes (T2D) increases with obesity. One possible explanation is that pleiotropic genes affect risk of both… Expand
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2005
2005
How many genes encode proteins involved in multiple cellular processes? Genetic pleiotropy becomes apparent when mutations in a… Expand
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2003
2003
Risk factors for coronary heart disease (CHD), including prethrombotic changes in hemostasis, cluster with the insulin resistance… Expand
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1984
1984
A model of selection is described in which optimizing phenotypic selection is combined with pleiotropic overdominance. Thus, the… Expand
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1973
1973
THREE methods are available for the genetic analysis of continuous variables in human populations. One is the biometrical… Expand
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