Platelet Factor 4, human

Known as: Small-Inducible Cytokine B4, Small Inducible Cytokine Subfamily B, Member 4, Chemokine (C-X-C motif) Ligand 4 
Platelet factor 4 (101 aa, ~11 kDa) is encoded by the human PF4 gene. This protein is involved in the negative regulation of endothelial cell… (More)
National Institutes of Health

Papers overview

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2011
2011
We investigated possible cellular receptors for the human CXC chemokine platelet factor-4 variant/CXCL4L1, a potent inhibitor of… (More)
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Highly Cited
2009
Highly Cited
2009
Atherosclerosis is characterized by chronic inflammation of the arterial wall due to chemokine-driven mononuclear cell… (More)
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Highly Cited
2007
Highly Cited
2007
Early tumor detection and intervention are important determinants of survival in patients with cancer. We have recently reported… (More)
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Highly Cited
2004
Highly Cited
2004
Platelet factor-4 (PF-4)/CXCL4 was the first chemokine described to inhibit neovascularization. Here, the product of the… (More)
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Highly Cited
2000
Highly Cited
2000
Chemokines are mediators in inflammatory and autoimmune disorders. Aminoterminal truncation of chemokines results in altered… (More)
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Highly Cited
1996
Highly Cited
1996
Neovascularization is a feature of a variety of pathological processes. We compared the characteristics of vascular endothelial… (More)
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Highly Cited
1996
Highly Cited
1996
Pre-B-cell growth-stimulating factor/ stromal cell-derived factor 1 (PBSF/SDF-1) is a member of the CXC group of chemokines that… (More)
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Highly Cited
1995
Highly Cited
1995
The 121-amino acid form of vascular endothelial growth factor (VEGF121) and the 165-amino acid form (VEGF165) are mitogenic for… (More)
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Highly Cited
1990
Highly Cited
1990
Recombinant human platelet factor-4 (rhPF4), purified from Escherichia coli, inhibited blood vessel proliferation in the chicken… (More)
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Highly Cited
1985
Highly Cited
1985
Interferons are a family of proteins first identified by their ability to induce cellular resistance to infection by many viruses… (More)
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