Platelet-Derived Growth Factor alpha Receptor

Known as: Receptor, PDGF alpha, CD140a Antigen, PDGF-R-alpha 
A PDGF receptor that binds specifically to both PDGF-A chains and PDGF-B chains. It contains a protein-tyrosine kinase activity that is involved in… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
A subset of gastrointestinal stromal tumors (GISTs) lack gain-of-function mutations in c-KIT and PDGFRalpha. These so-called wild… (More)
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2006
2006
Activated fibroblasts are thought to play important roles in the progression of many solid tumors, but little is known about the… (More)
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Highly Cited
2005
Highly Cited
2005
Platelet-derived growth factor receptor alpha (PDGFRalpha) is a type III receptor tyrosine kinase that is expressed on a variety… (More)
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Highly Cited
2004
Highly Cited
2004
Most gastrointestinal stromal tumors (GISTs) carry activating mutations of the KIT gene encoding the receptor tyrosine kinase KIT… (More)
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Highly Cited
2004
Highly Cited
2004
PURPOSE We identified the platelet-derived growth factor receptor alpha (PDGFRalpha) as an ovarian cancer-specific gene by… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Idiopathic hypereosinophilic syndrome involves a prolonged state of eosinophilia associated with organ dysfunction. It… (More)
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2002
2002
OBJECTIVE To determine whether the expression of platelet derived growth factor alpha receptor (PDGFRalpha) in low grade… (More)
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Highly Cited
1999
Highly Cited
1999
The Cbl proto-oncogene product has emerged as a novel negative regulator of receptor and non-receptor tyrosine kinases. Our… (More)
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Highly Cited
1998
Highly Cited
1998
The Cbl protooncogene product has emerged as a negative regulator of receptor and nonreceptor tyrosine kinases. We recently… (More)
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Highly Cited
1997
Highly Cited
1997
In gastrulating embryos, various types of cells are generated before differentiation into specific lineages. The mesoderm of the… (More)
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