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Platelet-Derived Growth Factor Receptor Alpha, human

Known as: EC 2.7.1.112, CD140 Antigen-Like Family Member A, Platelet-Derived Growth Factor Alpha Receptor 
Platelet-derived growth factor receptor alpha (1089 aa, ~123 kDa) is encoded by the human PDGFRA gene. This protein is involved in ligand binding… 
National Institutes of Health

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Cell Differentiation processCell Migration PathwayCell ProliferationEnzyme Gene

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Platelet-Derived Growth Factor alpha Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Generation of the Fip1l1–Pdgfra fusion gene using CRISPR/Cas genome editing
The FIP1L1-PDGFRA fusion gene is an important oncogenic driver of chronic eosinophilic leukemia, now referred to as the WHO… 
2015
2015
MicroRNA-219-5p functions as a tumor suppressor partially by targeting platelet-derived growth factor receptor alpha in colorectal cancer.
Platelet-derived growth factor receptor (PDGFR) signaling pathway was involved in the progress of colorectal cancer (CRC). By… 
2013
2013
Telocytes express PDGFRa in the human gastrointestinal tract
Telocytes (TC), a cell population located in the connective tissue of many organs of humans and laboratory mammals, are… 
2011
2011
Beginning of personalized medicine in Panama: Molecular and pathological characteristics of gastrointestinal stromal tumors from archival paraffin-embedded tissue.
This is the first study from Central America to analyze genetic mutations and histopathological features associated with… 
Review
2010
Review
2010
Les anomalies moléculaires dans les lymphomes
Numerous molecular abnormalities have been described in lymphomas. They are of diagnostic and prognostic value and are taken into… 
1996
1996
Cell-type-specific expression of the platelet-derived growth factor alpha receptor: a role for GATA-binding protein
Platelet-derived growth factor alpha receptor (PDGF alpha R) is a transmembrane tyrosine kinase receptor for all three existing… 
1995
1995
Molecular cloning and functional characterization of the human platelet-derived growth factor alpha receptor gene promoter.
Expression of the platelet-derived growth factor alpha receptor (PDGF alpha R) is strictly regulated during mammalian development… 
1995
1995
A 1.8-Mb YAC contig spanning three members of the receptor tyrosine kinase gene family (Pdgfra, Kit, and Flk1) on mouse chromosome 5.
1994
1994
Structural analysis of chromosomal rearrangements associated with the developmental mutations Ph, W19H, and Rw on mouse chromosome 5.
We are studying the chromosomal structure of three developmental mutations, dominant spotting (W), patch (Ph), and rump white (Rw… 
1994
1994
Mouse rump-white mutation associated with an inversion of Chromosome 5
The rump-white (Rw) mutation in the mouse was previously mapped as part of a cluster of spotting genes on Chromosome (Chr) 5 that… 
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