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Plasma Kallikrein

Known as: Kallikrein, Plasma, Plasma Kallikrein Precursor, Fletcher Factor 
A peptidohydrolytic enzyme that is formed from PREKALLIKREIN by FACTOR XIIA. It activates FACTOR XII; FACTOR VII; and PLASMINOGEN. It is selective… 
National Institutes of Health

Related topics

Related topics

22 relations
Blood coagulationEnzyme GeneGlycoproteinsHomo sapiens

Broader (2)

CoagulantsKininogenase

Papers overview

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2001
2001
Synthetic Peptides and Fluorogenic Substrates Related to the Reactive Site Sequence of Kunitz-Type Inhibitors Isolated from Bauhinia: Interaction with Human Plasma Kallikrein
Abstract We have previously described Kunitz-type serine proteinase inhibitors purified from Bauhinia seeds. Human plasma… 
1987
1987
Immunoblotting Studies of Coagulation Factor XII, Plasma Prekallikrein, and High Molecular Weight Kininogen
Immunoblotting techniques for the qualitative and quantitative analysis of FXII, PK, and HMWK in whole plasma are presented… 
1985
1985
Rat plasma kallikrein clearance by perfused rat liver.
Previous studies have shown that perfused rat liver in situ is able to clear recirculating rat plasma kallikrein (RPK) in two… 
1984
1984
Guinea pig plasma kallikrein as a vascular permeability enhancement factor. Its dependence on kinin generation and regulation mechanisms in vivo.
Plasma kallikrein (mol wt 80,000) was purified from guinea pig plasma, and it caused vascular permeability enhancement when… 
Highly Cited
1981
Highly Cited
1981
Mapping the active sites of bovine thrombin, factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: development of new sensitive…
The subsite specificities of bovine factor IXa, factor Xa, factor XIa, factor XIIa, thrombin, plasma kallikrein, and trypsin were… 
Highly Cited
1980
Highly Cited
1980
Studies on components of the plasma kallikrein-kinin system in plasma samples from normal individuals and patients with septic shock.
Components of the plasma kallikrein-kinin system were determined in plasma samples from ten healthy subjects and eight patients… 
1980
1980
Studies on some coagulation factors (Hageman factor, plasma prekallikrein, and high molecular weight kininogen) in the normal newborn.
Normal newborn infants have a prolonged partial thromboplastin time compared to that of older infants or adults. This finding has… 
1979
1979
Determination of prekallikrein in plasma by means of a chromogenic tripeptide substrate for plasma kallikrein.
A method for plasma prekallikrein determination utilizing a chromogenic tripeptic substrate is presented. The method has a good… 
1978
1978
Deficiency of factor XII-dependent plasminogen proactivator in prekallikrein-deficient plasma.
Normal human plasma contains a factor XII (Hageman factor)-dependent plasminogen proactivator in its gamma globulin fraction. On… 
1975
1975
Alteration of factor VII activity by activated Fletcher factor (a plasma kallikrein): a potential link between the intrinsic and extrinsic blood-clotting systems.
Although surface contact is known to accelerate the one-stage prothrombin time of human plasma through the participation of…