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Mutations in the genes for amyloid precursor protein (APP) and presenilins (PS1, PS2) increase production of β-amyloid 42 (Aβ42… Expand Alzheimer's disease (AD) involves amyloid β (Aβ) accumulation, oxidative damage, and inflammation, and risk is reduced with… Expand SummaryEighty-three brains obtained at autopsy from nondemented and demented individuals were examined for extracellular amyloid… Expand This report describes the first human study of a novel amyloid‐imaging positron emission tomography (PET) tracer, termed… Expand Amyloid plaques are a neuropathological hallmark of Alzheimer's disease (AD), but their relationship to neurodegeneration and… Expand Amyloid-β peptide (Aβ) seems to have a central role in the neuropathology of Alzheimer's disease (AD). Familial forms of the… Expand Transgenic mice overexpressing the 695-amino acid isoform of human Alzheimer β-amyloid (Aβ) precursor protein containing a Lys670… Expand ALZHEIMER'S disease (AD) is the most common cause of progressive intellectual failure in aged humans. AD brains contain numerous… Expand During the course of our immunohistochemical studies on the change of lipids in Alzheimer's disease brains by using antibody to… Expand Alzheimer's disease1 is characterized by a widespread functional disturbance of the human brain. Fibrillar amyloid proteins are… Expand