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Piritrexim Isethionate

Known as: 2,4-Diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido(2,3-d)pyrimidine mono(2-hydroxyethanesulfonate), BW-301U Isethionate 
The isethionate salt of piritrexim, a synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the… 
National Institutes of Health

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2001
2001
Approaches to Soft Drug Analogues of Dihydrofolate Reductase Inhibitors Design and Synthesis BY MALIN GRAFFNER NORDBERG ACTA UNIVERSITATIS UPSALIENSIS UPPSALA 2001
Graffner Nordberg, M. 2001. Approaches to Soft Drug Analogues of Dihydrofolate Reductase Inhibitors. Design and Synthesis. Acta… 
1993
1993
A multicentre 12‐week open study of a lipid‐soluble folate antagonist, piritrexim in severe psoriasis
An open, 12‐week, multicentre study was conducted to assess the efficacy of piritrexim isethionate in the treatment of severe… 
1973
1973
Effects of anions and cations on the resting membrane potential of internally perfused barnacle muscle fibres
1. Single barnacle muscle fibres from Megabalanus psittacus (Darwin) were internally perfused with a number of K salt solutions… 
1961
1961
The affinity of hydroxystilbamidine for psoriatic lesions.
Recent clinical trials with 2-hydroxystilbamidine isethionate in psoriasis (11 cases) showed that the drug becomes localized in… 
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