Picryl Chloride

Known as: Picryl Chloride [Chemical/Ingredient], 2,4,6-Trinitro-1-chlorobenzene, Trinitrochlorobenzene 
A hapten that generates suppressor cells capable of down-regulating the efferent phase of trinitrophenol-specific contact hypersensitivity… (More)
National Institutes of Health

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Highly Cited
2003
Highly Cited
2003
Experiments on the sensitization of guinea pigs with simple chemical compounds are described. Positive effects were obtained by… (More)
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Highly Cited
2003
Highly Cited
2003
TAK1, a member of the mitogen-activated kinase kinase kinase (MAPKKK) family, participates in proinflammatory cellular signaling… (More)
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Highly Cited
2000
Highly Cited
2000
The immunosuppressive drug, mycophenolate mofetil (MMF), has been successfully introduced in allogeneic transplantation medicine… (More)
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Highly Cited
1997
Highly Cited
1997
After application of haptens to the skin, Langerhans cells (LC), i.e. immature dendritic cells (DC) in the skin, move to… (More)
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Highly Cited
1996
Highly Cited
1996
Mice rendered deficient in IL-1 beta by gene targeting in embryonic stem cells develop and grow normally in a protected… (More)
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Highly Cited
1995
Highly Cited
1995
To determine whether IL-12 serves as a regulator of contact sensitivity reactions, mice were painted with either 1.0… (More)
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Highly Cited
1994
Highly Cited
1994
Interleukin 10 (IL-10) is released during the induction phase of contact sensitivity and was shown in prior functional studies to… (More)
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Highly Cited
1993
Highly Cited
1993
Langerhans cells (LC) are Ag-presenting cells required for induction of primary immune responses in skin. After activation by Ag… (More)
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Highly Cited
1991
Highly Cited
1991
We examined the role of cytokines in the cutaneous response to the application of trinitrochlorobenzene (TNCB) in both… (More)
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Highly Cited
1990
Highly Cited
1990
After short term culture (2 to 3 days), Langerhans cells (LC) exhibit increased class II MHC Ag and become more potent APC than… (More)
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