FAQ

Phosphotyrosine Binding Domain

Known as: PTB, PID, PTB Domain 
Phosphotyrosine binding (PTB) domains are 100-150 residue modules that commonly bind Asn-Pro-X-Tyr motifs. The PTB domains of the docking proteins… (More)

Topic mentions per year

Topic mentions per year

1968-2017
010020019682017

Related topics

Related topics

10 relations
Amyloid Beta A4 Precursor Protein-Binding Family A Member 1Amyloid Beta A4 Precursor Protein-Binding Family A Member 2Amyloid Beta A4 Precursor Protein-Binding Family A Member 3DOK1 protein, human
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Related mentions per year

Related mentions per year

1968-2018
1960198020002020
Phosphotyrosine Binding Domain
PTPN11 protein, human
PTPN22 protein, human
PTPN1 protein, human
PTPN6 protein, human
PTPN12 protein, human

Papers overview

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Review
2016
Review
2016
Does Maternal Vitamin D Deficiency Increase the Risk of Preterm Birth: A Meta-Analysis of Observational Studies
There are disagreements among researchers about the association between vitamin D deficiency during pregnancy and preterm birth… (More)
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Highly Cited
2010
Highly Cited
2010
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB
To gain global insights into the role of the well-known repressive splicing regulator PTB, we analyzed the consequences of PTB… (More)
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Highly Cited
2007
Highly Cited
2007
A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.
Many metazoan gene transcripts exhibit neuron-specific splicing patterns, but the developmental control of these splicing events… (More)
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Highly Cited
2005
Highly Cited
2005
Structure of PTB bound to RNA: specific binding and implications for splicing regulation.
The polypyrimidine tract binding protein (PTB) is a 58-kilodalton RNA binding protein involved in multiple aspects of messenger… (More)
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2005
2005
The C2 Domain of PKCδ Is a Phosphotyrosine Binding Domain
In eukaryotic cells, the SH2 and PTB domains mediate protein-protein interactions by recognizing phosphotyrosine residues on… (More)
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Highly Cited
2004
Highly Cited
2004
A particle swarm optimization approach for optimum design of PID controller in AVR system
In this paper, a novel design method for determining the optimal proportional-integral-derivative (PID) controller parameters of… (More)
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Highly Cited
2004
Highly Cited
2004
Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay.
Polypyrimdine tract binding protein (PTB) is a regulator of alternative splicing, mRNA 3' end formation, mRNA stability and… (More)
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1996
1996
Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.
The Shc adaptor protein contains two phosphotyrosine [Tyr(P)]binding modules--an N-terminal Tyr(P) binding (PTB) domain and a C… (More)
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1996
1996
Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling.
Stimulation via the T-cell growth factor interleukin 2 (IL-2) leads to tyrosine phosphorylation of Shc, the interaction of Shc… (More)
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Highly Cited
1995
Highly Cited
1995
Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins.
In higher eukaryotes, the polypyrimidine-tract (Py-tract) adjacent to the 3' splice site is recognized by several proteins… (More)
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