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Phosphoinositide 3-Kinase Regulatory Subunit 5, human

Known as: Phosphoinositol 3-Kinase Regulatory Subunit 5, PIK3R5, PtdIns-3-Kinase P101 
Phosphoinositide 3-kinase regulatory subunit 5 (880 aa, ~97 kDa) is encoded by the human PIK3R5 gene. This protein plays a role in the regulation of… Expand
National Institutes of Health

Related topics

Related topics

18 relations
ApoptosisB Cell Receptor Signaling PathwayBrainERBB Family Signaling Pathway
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Broader (1)

Class Ib Phosphatidylinositol 3-Kinase, p101 Subunit

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
miR-210-5p promotes epithelial–mesenchymal transition by inhibiting PIK3R5 thereby activating oncogenic autophagy in osteosarcoma cells
Osteosarcoma (OS) is a malignant bone tumor which occurs mainly in adolescents with frequent pulmonary metastasis and a high… Expand
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2017
2017
Phosphoinositol 3‐phosphate acts as a timer for reactive oxygen species production in the phagosome
Production of reactive oxygen species (ROS) in the phagosome by the NADPH oxidase is critical for mammalian immune defense… Expand
2016
2016
Maternal and fetal genomes interplay through phosphoinositol 3-kinase(PI3K)-p110α signaling to modify placental resource allocation
Significance During pregnancy, nutrients are required for fetal growth and for the mother to maintain the pregnancy. The placenta… Expand
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2013
2013
In silico analysis of influence of the missense mutation P629S on the molecular interaction and 3D properties of PIK3R5
PIK3R5 is the regulatory subunit of Phosphoinositide 3-kinase γ (PI3Kγ) that is responsible for phosphory-lating membrane lipids… Expand
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2008
2008
Molecular determinants of activation and membrane targeting of phosphoinositol 4-kinase IIbeta.
Mammalian cells contain two isoforms of the type II PI4K (phosphoinositol 4-kinase), PI4KIIalpha and beta. These 55 kDa proteins… Expand
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