Phosphodiesterase I

Known as: 5' Nucleotidephosphodiesterase, Orthophosphoric Diester Phosphohydrolase, Phosphohydrolase, Orthophosphoric Diester 
A phosphoric diester hydrolase that removes 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated OLIGONUCLEOTIDES. It has low activity… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1968-2018
010203019682018

Papers overview

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Highly Cited
2012
Highly Cited
2012
MicroRNAs (miRNAs) are small noncoding RNAs that regulate eukaryotic gene expression by binding to regions of imperfect… (More)
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Highly Cited
2010
Highly Cited
2010
DNA interstrand crosslinks (ICLs) are highly toxic because they block the progression of replisomes. The Fanconi Anemia (FA… (More)
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Highly Cited
2005
Highly Cited
2005
The final step of triacylglycerol biosynthesis is catalyzed by acyl CoA:diacylglycerol acyltransferase (DGAT) enzymes. The two… (More)
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Highly Cited
2004
Highly Cited
2004
Werner syndrome (WS) is characterized by features of premature aging and is caused by loss of the RecQ helicase protein WRN. WS… (More)
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Highly Cited
2000
Highly Cited
2000
The phosphate starvation response in Bacillus subtilis was analyzed using two-dimensional (2D) polyacrylamide gel electrophoresis… (More)
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Highly Cited
1998
Highly Cited
1998
MRE11 and RAD50 are known to be required for nonhomologous joining of DNA ends in vivo. We have investigated the enzymatic… (More)
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Highly Cited
1998
Highly Cited
1998
Genetic studies in yeast have indicated a role of the RAD50 and MRE11 genes in homologous recombination, telomere length… (More)
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Highly Cited
1991
Highly Cited
1991
Although the polymerase chain reaction (1,2) (PCR) can be used to produce a large amount of a specific DNA from a complex source… (More)
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Highly Cited
1987
Highly Cited
1987
A chemically modified phage T7 DNA polymerase has three properties that make it ideal for DNA sequencing by the chain-termination… (More)
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Highly Cited
1985
Highly Cited
1985
A simple new procedure was described for producing a sequential series of overlapping clones for use in DNA sequencing. The… (More)
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