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Phosphinic acid derivatives exhibit diverse biological activities and a high degree of structural diversity, rendering them a… Expand Given the wide application of positron emission tomography (PET), positron‐emitting metal radionuclides have received much… Expand The actions of a series of derivatives of 3-aminopropyl-phosphinic acid as baclofen agonists and antagonists have been examined… Expand Phosphinic acid-based inhibitors of MMP-13 have been investigated with the aim of identifying potent inhibitors with high… Expand In 1987, 25 years after the synthesis of the potent and selective GABAB agonist baclofen (1), Kerr et al. described the first… Expand The antispastic agent and muscle relaxant baclofen 1 is a potent and selective agonist for bicuculline-insensitive GABAB… Expand NEW MATERIAL: The compound (salt) of the formula I [R is H, a 1-4C alkyl; Z is the formula (CH 2 ) n (n is 0-2); X is H, CL, F… Expand NEW MATERIAL: A compd. represented by formula I (wherein X 1 to X 3 are each H, F, etc.; R is a group represented by formula II… Expand