Phosphatidylinositol Glycan

Known as: Glycan, Phosphatidylinositol, PI Glycan, PI-Glycan 
 
National Institutes of Health

Related topics

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5 relations

Broader (1)

Glycosylphosphatidylinositols
PIGA genePIGL genePIGN genePIGW gene

Papers overview

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Review
2011
Review
2011
Treatment of paroxysmal nocturnal hemoglobinuria in the era of eculizumab.
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life-threatening and debilitating clonal blood disorder caused by an… (More)
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2006
2006
Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in…
Based on the oncogenic role of phosphatidylinositol glycan (PIG) class U in human tumors, we explored the role of two additional… (More)
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2001
2001
Phosphatidylinositol Glycan ( PIG ) Anchored Membrane Proteins
Secreted proteins are processed from a nascent form that contains an NHz-terminal signal peptide. During processing, the latter… (More)
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Review
1995
Review
1995
Function of human Fc gamma RIIA and Fc gamma RIIIB.
Fc gamma RIIA (CD32), a conventional type I transmembrane protein, and Fc gamma RIIIB (CD16B), which has a glycan… (More)
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Highly Cited
1994
Highly Cited
1994
Somatic mutations and cellular selection in paroxysmal nocturnal haemoglobinuria
Patients with paroxysmal nocturnal haemoglobinuria (PNH) have in their blood two red-cell populations, one normal and one… (More)
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1994
1994
Mutations in the PIG-A gene causing partial deficiency of GPI-linked surface proteins (PNH II) in patients with paroxysmal nocturnal haemoglobinuria.
Paroxysmal nocturnal haemoglobinuria (PNH) is due to the absence or marked reduction of glycan phosphatidylinositol (GPI… (More)
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1994
1994
Genomic organization of the X-linked gene (PIG-A) that is mutated in paroxysmal nocturnal haemoglobinuria and of a related autosomal pseudogene mapped to 12q21.
The PIG-A gene, whose product is involved in one of the early steps in the synthesis of glycan phosphatidylinositol (GPI) anchors… (More)
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1990
1990
The PIG-anchoring defect in NK lymphocytes of PNH patients.
Paroxysmal nocturnal hemoglobinuria (PNH) is clinically characterized by intravascular hemolysis, hemoglobinuria, iron deficiency… (More)
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1989
1989
Mechanisms for regulating expression of membrane isoforms of Fc gamma RIII (CD16).
Granulocyte and natural killer (NK) cell Fc receptors for immunoglobulin G (CD16) differ in only a few amino acids, yet have… (More)
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Highly Cited
1988
Highly Cited
1988
The major Fc receptor in blood has a phosphatidylinositol anchor and is deficient in paroxysmal nocturnal haemoglobinuria
Fc receptors on phagocytic cells in the blood mediate binding and clearance of immune complexes, phagocytosis of antibody… (More)
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