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Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta Isoform, human

Known as: PIK3CD, PI3-Kinase p110 Subunit Delta, PI3Kdelta 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (1044 aa, ~119 kDa) is encoded by the human PIK3CD gene. This protein… 
National Institutes of Health

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19 relations
1-Phosphatidylinositol 3-KinaseApoptosisB Cell Receptor Signaling PathwayERBB Family Signaling Pathway

Papers overview

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2016
2016
Abstract 4635: Comparative cancer cell line profiling differentiates the mechanism of action of different PI3K/mTOR, Aurora kinase and EZH2 inhibitors
[purpose] Profiling of drug candidates in cell line panels is an important tool to compare the selectivity and targeting of new… 
2013
2013
Investigating the effects of CSF-1R and PI3Kdelta inhibition on a breast cancer bone metastasis model
2013
2013
Abstract 603: CAL-101 acts synergistic with arsenic trioxide in chronic lymphocytic leukemia by preventing p21 phosphorylation through AKT1.
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC Chronic lymphocytic leukemia (CLL) is the most… 
2012
2012
The PI3K catalytic subunit p110-delta is a crucial mediator of leukemia-associated mutant PTPN11 -induced GM-CSF hypersensitivity
2006
2006
The contribution of PI 3-K and its catalytic isoform, p110delta, towards neuronal growth cone motility.