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Phosphatidate Phosphatase

Known as: Phosphohydrolase, Phosphatidate, Phosphatase, Phosphatidic Acid, 3-sn-Phosphatidate phosphohydrolase 
A phosphomonoesterase involved in the synthesis of triacylglycerols. It catalyzes the hydrolysis of phosphatidates with the formation of… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Lipids are essential building blocks synthesized by complex molecular pathways and deposited as lipid droplets (LDs) in cells… Expand
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Review
2013
Review
2013
Yeast Pah1p phosphatidate phosphatase (PAP) catalyzes the penultimate step in the synthesis of triacylglycerol. PAP plays a… Expand
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Highly Cited
2011
Highly Cited
2011
The nutrient- and growth factor-responsive kinase mTOR complex 1 (mTORC1) regulates many processes that control growth, including… Expand
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Highly Cited
2010
Highly Cited
2010
Regulation of membrane lipid composition is crucial for many aspects of cell growth and development. Lipins, a novel family of… Expand
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Highly Cited
2007
Highly Cited
2007
The Saccharomyces cerevisiae PAH1-encoded Mg2+-dependent phosphatidate phosphatase (PAP1, 3-sn-phosphatidate phosphohydrolase, EC… Expand
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Review
2006
Review
2006
Phosphatidate phosphatase (PAP) enzymes catalyze the dephosphorylation of phosphatidate, yielding diacylglycerol and inorganic… Expand
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Highly Cited
2006
Highly Cited
2006
We previously identified mutations in the Lpin1 gene, encoding lipin-1, as the underlying cause of lipodystrophy in the fatty… Expand
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Highly Cited
2006
Highly Cited
2006
Phosphorylation of the conserved lipin Pah1p/Smp2p in Saccharomyces cerevisiae was previously shown to control transcription of… Expand
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Review
1998
Review
1998
In eukaryotes, many receptor agonists use phospholipase-generated lipids as intracellular messengers. Receptor occupation… Expand
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Highly Cited
1982
Highly Cited
1982
Autopsy findings suggest that lung surfactant is damaged in the adult respiratory distress syndrome. In the present study 225… Expand
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