Philadelphia chromosome positive chronic myelogenous leukemia

Known as: Ph' Chromosome Positive Chronic Myelogenous Leukemia, Ph' Chromosome Positive Chronic Myeloid Leukemia, Ph1 positive CML 
A chronic myelogenous leukemia characterised by the t(9;22)(q34;q11) chromosomal translocation, resulting in the presence of the Philadelphia… (More)
National Institutes of Health

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ABL1 geneAnemiaBCR-ABL Fusion GeneBone Marrow
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Papers overview

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2005
2005
Rearrangements in the p 53 Gene in Philadelphia Chromosome Positive Chronic Myelogenous Leukemia
Molecular structural analysis of the p53 gene in patients with Philadelphia chromosome-positive chronic myelogenous leukemia (CML… (More)
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Highly Cited
2004
Highly Cited
2004
Novel type V staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC.
Staphylococcal cassette chromosome mec (SCCmec) is a mobile genetic element composed of the mec gene complex, which encodes… (More)
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Highly Cited
2004
Highly Cited
2004
The Master Sex-Determination Locus in Threespine Sticklebacks Is on a Nascent Y Chromosome
BACKGROUND Many different environmental and genetic sex-determination mechanisms are found in nature. Closely related species can… (More)
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Highly Cited
1994
Highly Cited
1994
A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro
We report here a chromosomal protein that plays an essential role in mitotic chromosome condensation in Xenopus egg extracts. Two… (More)
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Highly Cited
1991
Highly Cited
1991
Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome
X-CHROMOSOME inactivation in mammals is a regulatory phenomenon whereby one of the two X chromosomes in female cells is… (More)
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1989
1989
Rearrangements in the p53 gene in Philadelphia chromosome positive chronic myelogenous leukemia.
Molecular structural analysis of the p53 gene in patients with Philadelphia chromosome-positive chronic myelogenous leukemia (CML… (More)
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Highly Cited
1988
Highly Cited
1988
Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.
The Philadelphia chromosome is present in more than 95% of chronic myeloid leukemia patients and 13% of acute lymphocytic… (More)
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Highly Cited
1984
Highly Cited
1984
Construction and applications of a highly transmissible murine retrovirus shuttle vector
We develop a murine retrovirus shuttle vector system for the efficient introduction of selectable and nonselectable DNA sequences… (More)
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1981
1981
Erythroblastic transformation of Philadelphia chromosome (Ph1)-positive chronic myelogenous leukemia associated with marked chromosomal rearrangements.
In a 22-year-old female with Philadelphia chromosome (Ph1)-positive chronic myelogenous leukemia (CML) a tumor consisting of… (More)
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Highly Cited
1973
Highly Cited
1973
A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining
CELLS from nine consecutive patients with chronic myelogenous leukaemia (CML) have been analysed with quinacrine fluorescence and… (More)
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