Phase I/II Trial

Known as: 1-2, Trial Phase 1-2, Trial Phase 1/2 
A clinical research protocol designed to study the safety, dosage levels and response to new treatment. Phase I/II trials combine a Phase I and a… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
BACKGROUND Ceritinib is a next-generation anaplastic lymphoma kinase (ALK) inhibitor, which has shown robust anti-tumour efficacy… (More)
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Review
2016
Review
2016
Purpose – Building information modelling (BIM) in facilities management (FM) applications is an emerging area of research based… (More)
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Highly Cited
2012
Highly Cited
2012
While high-level data parallel frameworks, like MapReduce, simplify the design and implementation of large-scale data processing… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND MDV3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents… (More)
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Highly Cited
2008
Highly Cited
2008
This paper describes the semiglobal matching (SGM) stereo method. It uses a pixelwise, mutual information (Ml)-based matching… (More)
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Highly Cited
2007
Highly Cited
2007
MNI coordinates determined using SPM2 and FSL/FLIRT with the ICBM-152 template were compared to Talairach coordinates determined… (More)
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Review
1998
Review
1998
The number of prokaryotes and the total amount of their cellular carbon on earth are estimated to be 4-6 x 10(30) cells and 350… (More)
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Highly Cited
1990
Highly Cited
1990
In this issue of the journal, Kreisle and associates (/) report that angiogenesis and growth of B16 melanoma decreased with age… (More)
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Highly Cited
1985
Highly Cited
1985
In postmortem brain specimens from 163 clinically diagnosed cases of Huntington's disease (HD) the striatum exhibited marked… (More)
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Highly Cited
1979
Highly Cited
1979
Density of synaptic profiles in layer 3 of middle frontal gyrus was quantitated in 21 normal human brains ranging from newborn to… (More)
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