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Pharmacokinetic Concentration Domain

Known as: PC, Pharmacokinetic Concentration 
A subject domain utilized for the submission of information encompassing and representing data, vocabulary or records related to pharmacokinetic… 
National Institutes of Health

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3 relations
CDISC SDTM Submission Domain Abbreviation TerminologyCDISC SEND Domain Abbreviation TerminologyClinical Data Interchange Standards Consortium Terminology

Papers overview

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2020
2020
Pharmacokinetic Models to Characterize the Absorption Phase and the Influence of a Proton Pump Inhibitor on the Overall Exposure of Dacomitinib
Introduction: Dacomitinib is an epidermal growth factor receptor (EGFR) inhibitor approved for the treatment of metastatic non… 
2019
2019
Tubing-Free Microfluidic Microtissue Culture System Featuring Gradual, in vivo-Like Substance Exposure Profiles
In vitro screening methods for compound efficacy and toxicity to date mostly include cell or tissue exposure to preset constant… 
2018
2018
Abstract LB-044: In vitro assessment of combination dosing regimens with in vivo like pharmacokinetic concentration profiles enabled by a microfluidic addition and removal device
Combination dosing regimens offer the opportunity to improve the efficacy or better manage the toxicity profile of approved drugs… 
2018
2018
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses.
There is an ever-increasing demand for the therapeutic drug monitoring of antibiotics in many clinical facilities, particularly… 
2014
2014
Phase I study of olaratumab in Japanese patients with advanced solid tumors
Olaratumab (IMC‐3G3) is a fully human IgG1 monoclonal antibody that selectively binds the external domain of human platelet… 
2013
2013
Analysis of level A in vitro-in vivo correlations for an extended-release formulation with limited bioavailability.
A two-stage, numerical deconvolution approach was employed to develop level A in vitro-in vivo correlations using data for three… 
2011
2011
Pharmacokinetic Evaluation of Voriconazole Treatment in Critically Ill Patients Undergoing Continuous Venovenous Hemofiltration
Introduction: Voriconazole represents an essential part of antimicrobial therapy in critically ill patients. The aim of this… 
2009
2009
Comparison of spectroscopically measured tissue alcohol concentration to blood and breath alcohol measurements.
Alcohol testing is an expanding area of interest due to the impacts of alcohol abuse that extend well beyond drunk driving… 
2001
2001
Some statistical issues in modelling pharmacokinetic data
A fundamental assumption underlying pharmacokinetic compartment modelling is that each subject has a different individual curve… 
1972
1972
[An electronic simulator for demonstration of pharmacokinetic concentration patterns].
  • P. Bättig
  • Arzneimittel-Forschung
  • 1972
  • Corpus ID: 32526910
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