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Pharmacogenomic Variants

Known as: Pharmacogenomic Variant, Pharmacokinetic Genetic Variants, Variant, Pharmacogenomic 
Naturally occurring genetic variations associated with drug response (e.g., dosage, extent and rate of metabolic processes). While these variants are… Expand
National Institutes of Health

Papers overview

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2018
2018
BackgroundVariability in genes implicated in drug pharmacokinetics or drug response can modulate treatment efficacy or predispose… Expand
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Highly Cited
2016
Highly Cited
2016
Importance Whole-exome sequencing (WES) has the potential to reveal tumor and germline mutations of clinical relevance, but the… Expand
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2016
2016
Pathogenic ESBL-producing E. coli lineages occur frequently worldwide, not only in a human health context but in animals and the… Expand
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2014
2014
SummaryIntroduction Sunitinib is a multikinase inhibitor active in various cancers types including renal cancers and endocrine… Expand
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Highly Cited
2012
Highly Cited
2012
Background Identifying predictive biomarkers of drug response is of key importance to improve therapy management and drug… Expand
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Highly Cited
2012
Highly Cited
2012
AIM Warfarin pharmacogenomic algorithms reduce dosing error, but perform poorly in non-European-Americans. Electronic health… Expand
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Highly Cited
2011
Highly Cited
2011
PurposePaclitaxel has a broad spectrum of anti-tumor activity and is useful in the treatment of ovarian, breast, and lung cancer… Expand
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2008
2008
Objectives Cisplatin is a widely used chemotherapeutic agent; however, nephrotoxicity and neuropathy are obstacles for drug… Expand
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2008
2008
Eric J Peters1,2 1UNC Institute for Pharmacogenomics and Individualized Therapy, Division of Pharmacotherapy and Experimental… Expand
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2008
2008
The IG20 gene undergoes alternative splicing resulting in the differential expression of six putative splice variants. Four of… Expand
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