Skip to search formSkip to main contentSkip to account menu

Pergolide Mesylate

Known as: 8beta-[(Methylthio)methyl]-6-propylergoline Monomethanesulfonate, Pergolide Mesylate [Chemical/Ingredient], Pergolide Methanesulfonate 
A semi-synthetic ergot derivative and a dopamine agonist with antiparkinson property. Pergolide mesylate binds to and activates dopamine receptor… 
National Institutes of Health

Related topics

Related topics

8 relations
Drug AllergyErgot AlkaloidsGilles de la Tourette syndromeParkinson Disease

Narrower (2)

LY-127809Permax

Broader (1)

Pergolide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Cardiac valve regurgitation with pergolide compared with nonergot agonists in Parkinson disease.
BACKGROUND Although most studies have suggested an increased risk of valvulopathy (primarily regurgitation) with pergolide… 
2005
2005
The long-lasting improvement of sexual dysfunction in patients with advanced, fluctuating Parkinson's disease induced by pergolide: evidence from the results of an open, prospective, one-year trial.
Highly Cited
2000
Highly Cited
2000
Long-term treatment of prolactin-secreting macroadenomas with pergolide.
Although most PRL-secreting pituitary tumors are microadenomas at presentation, many, and particularly those in men, are… 
1985
1985
Pergolide mesylate
In a 12-month open-label trial, pergolide mesylate was administered in doses with antiparkinsonian efficacy to six patients with… 
Highly Cited
1984
Highly Cited
1984
Chronic levodopa or pergolide administration induces down‐regulation of dopamine receptors in denervated striatum
Refractory response to dopamine (DA) agonists is a common problem in the treatment of Parkinson's disease. In rats with… 
1984
1984
Central dopamine receptors mediating pergolide-induced elevation of serum corticosterone in rats Characterization by the use of antagonists
1983
1983
Elevation of serum corticosterone in rats by dopamine agonists related in structure to pergolide.
Two chemical analogs of pergolide were examined to test further the idea that pergolide elevates serum corticosterone… 
1982
1982
Pergolide mesylate and idiopathic Parkinson disease
We studied the effects of pergolide mesylate in an open trial of 23 patients with idiopathic Parkinson disease (PD). All had… 
1982
1982
Reduction in size of prolactin-secreting tumours in men treated with pergolide.
The effect of pergolide mesylate was studied in two previously untreated men with large prolactinomas and exceptionally high… 
1981
1981
Pergolide mesylate: its effects on circulating anterior pituitary hormones in man.
Pergolide mesylate is a synthetic ergoline with dopamine agonist properties. The endocrine profile was studied in a double blind… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)