Peptide Nucleic Acids

Known as: peptide nucleic acid (PNA), Acids, Peptide Nucleic, peptide nucleic acid 
DNA analogs containing neutral amide backbone linkages composed of aminoethyl glycine units instead of the usual phosphodiester linkage of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
MicroRNAs are small noncoding RNAs that regulate many cellular processes in a post-transcriptional mode. MicroRNA knockdown by… (More)
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Highly Cited
2005
Highly Cited
2005
Lung cancer is one of the leading causes of the cancer death worldwide. Gefitinib is an inhibitor of the tyrosine kinase activity… (More)
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Highly Cited
2003
Highly Cited
2003
Cellular uptake of a family of cationic cell-penetrating peptides (examples include Tat peptides and penetratin) have been… (More)
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Review
2000
Review
2000
Synthetic molecules that can bind with high sequence specificity to a chosen target in a gene sequence are of major interest in… (More)
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Review
1999
Review
1999
Peptide Nucleic Acid (PNA) is a powerful new biomolecular tool with a wide range of important applications. PNA mimics the… (More)
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Highly Cited
1997
Highly Cited
1997
Mitochondrial DNA (mtDNA) is the only extrachromosomal DNA in humans. It is a small (16.5kb) genome which encodes 13 essential… (More)
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Highly Cited
1996
Highly Cited
1996
We report the inhibition of human telomerase activity by peptide nucleic acids (PNAs). PNAs recognize the RNA component of human… (More)
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Highly Cited
1994
Highly Cited
1994
The stability of a new type of DNA mimic, peptide nucleic acid (PNA) in human blood serum, Eschericia coli and Micrococcus luteus… (More)
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Highly Cited
1994
Highly Cited
1994
ALTHOUGH the importance of the nucleobases in the DNA double helix is well understood, the evolutionary significance of the… (More)
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Highly Cited
1992
Highly Cited
1992
Peptide nucleic acids (PNAs) are polyamide oligomers that can strand invade duplex DNA, causing displacement of one DNA strand… (More)
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