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Peptide Nucleic Acid Clamping

Known as: Peptide Nucleic Acid Clamp, PCR Clamp, Peptide Nucleic Acid-mediated Competitive-PCR Clamping 
A modification of the standard polymerase chain reaction that increases the ability to preferentially amplify mutant alleles in the presence of an… 
National Institutes of Health

Papers overview

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2012
2012
Optimization of peptide nucleic acid clamp PCR for K-Ras mutation in colon cancer
Objective To develop a sensitive,simple and stable method for K-Ras mutation detection in patients of colon cancer.Methods We… 
2012
2012
Picoliter droplet-based digital peptide nucleic acid clamp PCR and dielectric sorting for low abundant K-ras mutations
2012
2012
High prevalence of BRAFV600E mutation in the papillary thyroid carcinomas in Korea by peptide nucleic acid clamp real-time PCR
2011
2011
A syncronous coefficient of drag alteration (SCODA) based technique for sequence specific enrichment of nucleic acids
2010
2010
First-line gefitinib therapy for elder advanced non-small cell lung cancer patients with epidermal growth factor receptor mutations: Multicenter phase II trial (NEJ 003 study).
7561 Background: First line treatment by gefitinib for NSCLC patients with EGFR mutations has been validated by us (NEJ 002 Study… 
2008
2008
First-line gefitinib for poor PS patients with EGFR mutations
8070 Background: We had previously reported several phase II studies using good performance status (PS) patients (pts) with…