Peptide Nucleic Acid Clamping
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Objective:To identify colon cancer patients with occult lymph node metastases. Summary of Background Data:The prognostic value of… Expand Sensitive detection of tumor-specific point mutations is of interest in both the early detection of cancer and the monitoring of… Expand Purpose: Somatic B-RAF gene mutation has been identified in many malignancies and detected at a high frequency in cutaneous… Expand The detection of rare mutant DNA from a background of wild-type alleles usually requires laborious manipulations, such as… Expand The major problem of using somatic mutations as markers of malignancy is that the clinical samples are frequently containing a… Expand Background and aimsSince the introduction of endovascular aortic aneurysm repair (EVAR) for aortic aneurysms, the number of… Expand Emergence of lamivudine‐resistant variants, with amino acid substitutions in the Tyr‐Met‐Asp‐Asp (YMDD) motif of hepatitis B… Expand ABSTRACT Peptide nucleic acid (PNA)-mediated PCR clamping (H. Ørum, P. E. Nielsen, M. Egholm, R. H. Berg, O. Buchardt, and C… Expand Although much is known about the mechanisms of signal-mediated protein and RNA nuclear import and export, little is understood… Expand Hereditary hemochromatosis (HH), an iron overload disease, is the most common known inheritable disease. The most prevalent form… Expand