Pentylenetetrazole

Known as: 5H-Tetrazolo(1,5-a)azepine, 6,7,8,9-tetrahydro-, PENTYLENETETRAZOL, Pentetrazol 
A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Social avoidance and social phobia are core symptoms of various psychopathologies but their underlying etiology remains poorly… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2008
Highly Cited
2008
It has been suggested that free oxygen radicals play a role in the genesis of epilepsy and in post-seizure neuronal death. The… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Rodent seizure models have significantly contributed to our basic understanding of epilepsy. However, medically intractable forms… (More)
  • figure 1
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Cognitive impairment in epileptics may be a consequence of the epileptogenic process as well as antiepileptic medication. Thus… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The mammalian hippocampus is a highly plastic brain structure in which new neurons are generated throughout adulthood. Do these… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Pentylenetetrazole (PTZ) is a central nervous system convulsant that is thought, based on binding studies, to act at the… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Using a newly developed perfused rat brain model, we examined direct effects of each change in cerebral blood flow (CBF) and… (More)
  • figure 1
  • figure 2
  • figure 3
  • table 2
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Whereas neonatal seizures are a predictor of adverse neurological outcome, there is controversy regarding whether seizures simply… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Although seizure models using systemic administration of the chemoconvulsant pentylenetetrazol (PTZ) for induction of generalized… (More)
Is this relevant?
Highly Cited
1989
Highly Cited
1989
The selective non-competitive NMDA receptor antagonist, MK-801, potently blocked convulsions induced in the mouse by N-methyl-DL… (More)
Is this relevant?