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Through the cannabinoid receptor 1 (CB1), the endocannabinoid system plays a physiological role in maintaining the activity of… Expand Sigma-1 receptor (σ1R), an endoplasmic reticulum–chaperone protein, can modulate painful response after peripheral nerve injury… Expand We have developed novel asymmetric routes to (-)-9- epi-pentazocine and (-)-aphanorphine from a d-tyrosine derivative. The… Expand A simple, accurate and rapid spectrophotometric method has been developed for the assay of ritodrine (RTH) and pentazocine… Expand Pharmacological preconditioning with κ-opioid receptor agonists is proarrhythmic and exerts antipreconditioning effects in rats… Expand Opioid analgesia is influenced by many factors, including the sigma1 receptor system. Current studies show the importance of… Expand Multiple sigma receptor subtypes have been identified in the hippocampus, yet their physiological role remains largely undefined… Expand The effects of 19 opiate agonists and antagonists on kindled amygdaloid seizures in the rat were studied. The mu agonists tended… Expand The metabolism of pentazocine was studied in the rat following oral administration. After the enzymatic hydrolysis of the urine… Expand The equivalents of pA2 values were determined for morphine, pentazocine and etorphine using the antagonists, naloxone and… Expand