Pentamidine

Known as: P,P'-(pentamethylenedioxy)dibenzamidine, Pentamidin, 1,5-Bis(4-amidinophenoxy)pentane 
A synthetic derivative of amidine with antiprotozoal and antifungal activities. Although the precise mode of action of pentamidine is unclear, it… (More)

Topic mentions per year

Topic mentions per year

1943-2018
05010019432017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Myotonic dystrophy (DM) is a genetic disorder caused by the expression (as RNA) of expanded CTG or CCTG repeats. The alternative… (More)
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Highly Cited
2005
Highly Cited
2005
The diamidine pentamidine is used to treat leishmaniasis, trypanosomiasis, and Pneumocystis carinii pneumonia. Treatment may be… (More)
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2005
2005
Pentamidine, an antiprotozoal agent, has been traditionally known to cause QT prolongation and arrhythmias; however, its ionic… (More)
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2005
2005
Pentamidine was compared with meglumine antimoniate (Glucantime) for 80 patients with cutaneous leishmaniasis due to Leishmania… (More)
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Highly Cited
2004
Highly Cited
2004
The biochemical changes consequent to respiratory chain inhibition and their relationship to cell death in Leishmania spp. remain… (More)
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2003
2003
Pentamidine (PEN) is a second-line agent in the treatment of leishmaniasis whose mode of action and resistance is not well… (More)
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2002
2002
The PRL family oncogenic phosphatases are attractive targets for developing inhibitors as anticancer therapeutics given their… (More)
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Highly Cited
2001
Highly Cited
2001
  • S Bala Sundar
  • Tropical medicine & international health : TM…
  • 2001
Throughout the world, pentavalent antimonial compounds (Sb(v)) have been the mainstay of antileishmanial therapy for more than 50… (More)
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1992
1992
We compared the efficacy of amphotericin B and pentamidine isethionate in a prospective randomised trial in 120 uncomplicated and… (More)
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1976
1976
Sensitivity to pentamidine of bloodstream forms and culture forms of Trypanosoma brucei brucei, strains of this subspecies, and… (More)
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