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Penfluridol

Known as: 4-Piperidinol, 1-(4,4-bis(4-fluorophenyl)butyl)-4-(4-chloro-3-(trifluoromethyl)phenyl)-, Penfluridol [Chemical/Ingredient] 
One of the long-acting ANTIPSYCHOTIC AGENTS used for maintenance or long-term therapy of SCHIZOPHRENIA and other PSYCHOTIC DISORDERS.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Glioblastoma (GBM) is the most common brain tumor with poor survival rate. Our results show that penfluridol, an antipsychotic… Expand
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Highly Cited
2016
Highly Cited
2016
Metastasis of breast cancer, especially to the brain, is the major cause of mortality. The inability of anticancer agents to… Expand
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2016
2016
Pancreatic tumors exhibit enhanced autophagy as compared to any other cancer, making it resistant to chemotherapy. We evaluated… Expand
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Review
2013
Review
2013
BACKGROUND Antipsychotic agents are often used to treat neuropsychiatric symptoms (NPS) in dementia, although the literature is… Expand
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Highly Cited
2002
Highly Cited
2002
T-type calcium channels play critical roles in cellular excitability and have been implicated in the pathogenesis of a variety of… Expand
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Highly Cited
1994
Highly Cited
1994
The authors examined the affinities of 36 typical and atypical antipsychotic agents for the cloned rat 5-hydroxytryptamine-6 (5… Expand
Highly Cited
1993
Highly Cited
1993
The susceptibilities of isolates of Plasmodium falciparum from Nigeria and two reference cloned strains (D6 and W2) to mefloquine… Expand
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Highly Cited
1983
Highly Cited
1983
Antischizophrenic neuroleptic drugs of the diphenylbutylpiperidine class, which includes pimozide, fluspirilene, penfluridol, and… Expand
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Highly Cited
1982
Highly Cited
1982
Acidic phospholipids, unsaturated fatty acids and limited proteolysis mimic the activating effect of calmodulin on erythrocyte… Expand
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Highly Cited
1970
Highly Cited
1970
Abstract R 16341, 4-(4-chloro- a , a , a -trifluoro-m-tolyl)-1[4,4-bis(p-fluorophenyl)butyl]-4-piperidinol is a new member of the… Expand