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Glioblastoma (GBM) is the most common brain tumor with poor survival rate. Our results show that penfluridol, an antipsychotic… Expand Metastasis of breast cancer, especially to the brain, is the major cause of mortality. The inability of anticancer agents to… Expand Pancreatic tumors exhibit enhanced autophagy as compared to any other cancer, making it resistant to chemotherapy. We evaluated… Expand BACKGROUND
Antipsychotic agents are often used to treat neuropsychiatric symptoms (NPS) in dementia, although the literature is… Expand T-type calcium channels play critical roles in cellular excitability and have been implicated in the pathogenesis of a variety of… Expand The authors examined the affinities of 36 typical and atypical antipsychotic agents for the cloned rat 5-hydroxytryptamine-6 (5… Expand The susceptibilities of isolates of Plasmodium falciparum from Nigeria and two reference cloned strains (D6 and W2) to mefloquine… Expand Antischizophrenic neuroleptic drugs of the diphenylbutylpiperidine class, which includes pimozide, fluspirilene, penfluridol, and… Expand Acidic phospholipids, unsaturated fatty acids and limited proteolysis mimic the activating effect of calmodulin on erythrocyte… Expand Abstract R 16341, 4-(4-chloro- a , a , a -trifluoro-m-tolyl)-1[4,4-bis(p-fluorophenyl)butyl]-4-piperidinol is a new member of the… Expand