Pegylated Recombinant Human Interleukin-10 AM0010

Known as: AM0010, PEG-rHuIL-10 AM0010 
A covalent conjugate of recombinant human interleukin-10 (IL-10) and polyethylene glycol (PEG), with potential anti-fibrotic, anti-inflammatory… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2015-2017
01220152017

Papers overview

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2017
2017
Awoman in her 70s presented with a new 4-cm left upper lobe lung mass with hilar lymphadenopathy. Biopsy results demonstrated a… (More)
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2016
2016
Purpose Interleukin-10 (IL-10) stimulates the expansion and cytotoxicity of tumor-infiltrating CD8+ T cells and inhibits… (More)
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2016
2016
In the accompanying article, Naing et al report encouraging clinical results from a phase I trial of single-agent pegylated… (More)
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2016
2016
  • Cancer discovery
  • 2016
In a phase Ib trial, a combination of the experimental immunotherapy AM0010, a PEGylated form of the recombinant human cytokine… (More)
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2015
2015
Recent advances in immunoncology have dramatically changed the treatment options available to cancer patients. However, the… (More)
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2015
2015
Background In preclinical studies, PEGylated IL-10 (PEG-IL-10) but not non-PEG IL-10 induces tumor rejection by the directly… (More)
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