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Pegylated Human Recombinant Arginase 1 AEB1102
Known as:
AEB1102
, Pegylated Recombinant Arginase AEB1102
A recombinant modified form of the human enzyme arginase 1 (ARG1), in which cobalt is substituted for manganese as a cofactor, covalently attached to…
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National Institutes of Health
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1 relation
Broader (1)
Co-ArgI-PEG
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2017
2017
Abstract 3964: Reducing systemic arginine with arginase (AEB1102) therapy does not suppress the immune response induced by anti-PD-1 and anti-PD-L1, and exerts an additive anti-tumor and synergistic…
Giulia Agnello
,
S. Alters
,
D. Lowe
,
S. Rowlinson
2017
Corpus ID: 80157669
Tumor dependence on specific amino acids for survival and proliferation is well recognized and has been exploited effectively…
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