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- Current drug discovery technologies
Fluoroquinolones have been the centre of considerable scientific and clinical interest due to their broad spectrum… (More)
Therapeutic activity, pharmacokinetic and bioavailability on animals (inbred white mouse, rabbits) were evaluated for Ofloxacin… (More)
- Pharmaceutical Chemistry Journal
To the present day no solution has been found to the problem of treating bacterial meningites brought about by both Gram-negative… (More)
- Clinical & experimental ophthalmology
To study the efficacy of intravitreal pefloxacin in the management of suspected bacterial endophthalmitis.
1. The patient, a 59 year old woman, developed a state of acute excitation several hours after the administration of 400 mg of… (More)
An open, randomized clinical study was carried out to compare the clinical efficacy and safety of pefloxacin with that of… (More)
The efficacy of pefloxacin, a novel promising antibacterial drug of the group of fluoroquinolones, was studied on mice against… (More)
- The Journal of antimicrobial chemotherapy
In the treatment of patients with bacterial endophthalmitis, the intravitreal administration of antibiotics is suitable for… (More)
In an open, randomized study, the effect of pefloxacin (400 mg b.i.d.) was compared with that of cefotaxime (1 g t.i.d.) in the… (More)
Thirty hospitalized patients (22 men and eight women), aged between 15 and 41 years (mean = 25.4 years), with severe proven… (More)