Pazopanib Hydrochloride

Known as: 5-((4-((2,3-Dimethyl-2h-Indazol-6-Yl)Methylamino)Pyrimidin-2-yl)Amino)-2-Methylbenzenesulfonamide Monohydrochloride 
The hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2017
012320092017

Papers overview

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2018
2018
The anti-cancer drug pazopanib hydrochloride (PZH) has a very low aqueous solubility and a variable oral bioavailability. A new… (More)
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2017
2017
A simple, accurate, precise, sensitive and stability indicating RP-HPLC method has been developed for the determination of… (More)
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2017
2017
Purpose To compare the efficacy of microneedle-delivered suprachoroidal (SC) pazopanib to intravitreal (Ivit) delivery of… (More)
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2015
2015
BACKGROUND In many European jurisdictions, relative effectiveness assessments (REAs) of pharmaceuticals are performed during the… (More)
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Review
2013
Review
2013
The National Institute for Health and Clinical Excellence (NICE) invited the manufacturer of pazopanib hydrochloride… (More)
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Review
2012
Review
2012
Pazopanib and axitinib are both U.S. Food and Drug Administration approved ATP-competitive inhibitors of the vascular endothelial… (More)
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2011
2011
The color of active pharmaceutical ingredients (APIs) can be a critical quality attribute for pharmaceutical products. Color… (More)
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2010
2010
Understanding the origin and fate of organic impurities within the manufacturing process along with a good control strategy is an… (More)
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2009
2009
Pharmaceutical regulatory agencies are increasingly concerned with trace-level genotoxic impurities in drug substances, requiring… (More)
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2009
2009
OBJECTIVE To investigate pazopanib hydrochloride, a multitargeted kinase inhibitor, for treatment of choroidal neovascularization… (More)
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