Patch-Clamp Techniques

Known as: Patch Clamp Techniques, Technics, Patch-Clamp, Patch-Clamp Technique 
An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2017
020040019812017

Papers overview

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Highly Cited
2008
Highly Cited
2008
Calcium-dependent chloride channels are required for normal electrolyte and fluid secretion, olfactory perception, and neuronal… (More)
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Highly Cited
2006
Highly Cited
2006
The patch-clamp technique allows investigation of the electrical excitability of neurons and the functional properties and… (More)
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Highly Cited
1995
Highly Cited
1995
1. By the development of a new perforated patch method using gramicidin, the effects of GABA on neurones dissociated from the rat… (More)
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Highly Cited
1994
Highly Cited
1994
The purpose of this study was to examine whether insulin's effect to vasodilate skeletal muscle vasculature is mediated by… (More)
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Highly Cited
1990
Highly Cited
1990
1. Synaptically connected neurones were identified in the granule cell layer of slices of 17- to 21-day-old rat hippocampus… (More)
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Highly Cited
1989
Highly Cited
1989
(1) A preparation is described which allows patch clamp recordings to be made on mammalian central nervous system (CNS) neurones… (More)
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Highly Cited
1987
Highly Cited
1987
Single-channel currents were recorded with the patch-clamp technique from freshly dissociated vertebrate smooth muscle cells from… (More)
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Highly Cited
1987
Highly Cited
1987
1. Calcium currents in cultured dorsal root ganglion (d.r.g.) cells were studied with the whole-cell patch-clamp technique. Using… (More)
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Highly Cited
1986
Highly Cited
1986
Pancreatic islets of NMRI mice were dissociated into single cells which were kept in tissue culture for 1-3 days. The whole-cell… (More)
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Highly Cited
1981
Highly Cited
1981
1. The extracellular patch clamp method, which first allowed the detection of single channel currents in biological membranes… (More)
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