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Pancreatic Ductal Adenocarcinoma
Known as:
Ductal Adenocarcinoma of Pancreas
, Pancreas Ductal Adenocarcinoma
, Pancreatic Infiltrating Duct Carcinoma, NOS
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An infiltrating adenocarcinoma that arises from the epithelial cells of the pancreas. It affects males more often than females and the patients are…
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National Institutes of Health
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Related topics
Related topics
37 relations
Abdominal Pain
Acinar Cell Differentiation
BRCA2 Gene Mutation
BRCA2 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts.
Ela Elyada
,
M. Bolisetty
,
+19 authors
D. Tuveson
Cancer Discovery
2019
Corpus ID: 189814661
Cancer-associated fibroblasts (CAFs) are major players in the progression and drug resistance of pancreatic ductal adenocarcinoma…
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Highly Cited
2015
Highly Cited
2015
Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma
Richard A. Moffitt
,
Raoud Marayati
,
+15 authors
Jen Jen Yeh
Nature Genetics
2015
Corpus ID: 205350563
Pancreatic ductal adenocarcinoma (PDAC) remains a lethal disease with a 5-year survival rate of 4%. A key hallmark of PDAC is…
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Review
2012
Review
2012
Pancreatic ductal adenocarcinoma: long-term survival does not equal cure.
C. Ferrone
,
R. Pieretti-Vanmarcke
,
+10 authors
A. Warshaw
Surgery
2012
Corpus ID: 7677776
Highly Cited
2012
Highly Cited
2012
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
A. Biankin
,
N. Waddell
,
+123 authors
S. Grimmond
Nature
2012
Corpus ID: 4325398
Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed exome sequencing and copy number…
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Highly Cited
2011
Highly Cited
2011
Subtypes of Pancreatic Ductal Adenocarcinoma and Their Differing Responses to Therapy
E. Collisson
,
A. Sadanandam
,
+15 authors
J. Gray
Nature Network Boston
2011
Corpus ID: 1182304
Pancreatic ductal adenocarcinoma (PDA) is a lethal disease. Overall survival is typically 6 months from diagnosis. Numerous phase…
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Highly Cited
2007
Highly Cited
2007
MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis.
M. Bloomston
,
W. Frankel
,
+7 authors
C. Croce
Journal of the American Medical Association (JAMA…
2007
Corpus ID: 21700673
CONTEXT While global microRNA (miRNA) expression patterns of many embryologic, physiologic, and oncogenic processes have been…
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Review
2006
Review
2006
Genetics and biology of pancreatic ductal adenocarcinoma.
A. Hezel
,
Alec C. Kimmelman
,
B. Stanger
,
N. Bardeesy
,
R. DePinho
Genes & Development
2006
Corpus ID: 6543918
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in the United States with a median survival…
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Highly Cited
2005
Highly Cited
2005
Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice.
S. Hingorani
,
Lifu Wang
,
+6 authors
D. Tuveson
Cancer Cell
2005
Corpus ID: 32692960
Highly Cited
2003
Highly Cited
2003
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma.
A. Aguirre
,
N. Bardeesy
,
+5 authors
R. DePinho
Genes & Development
2003
Corpus ID: 8125371
Pancreatic ductal adenocarcinoma ranks among the most lethal of human malignancies. Here, we assess the cooperative interactions…
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Review
1996
Review
1996
Long-term survival after curative resection for pancreatic ductal adenocarcinoma. Clinicopathologic analysis of 5-year survivors.
K. Conlon
,
D. Klimstra
,
M. Brennan
Annals of Surgery
1996
Corpus ID: 31005981
OBJECTIVE The authors reviewed the clinicopathologic characteristics of patients who underwent resection with curative intent for…
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