Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Palonosetron hydrochloride

Known as: 1H-Benz(de)isoquinolin-1-one, 2-(3S)-1-azabicyclo(2.2.2)oct-3-yl-2,3,3a,4,5,6-hexahydro-, Monohydrochloride,(3aS)- 
The hydrochloride salt of palonosetron, a carbazole derivative and a selective serotonin receptor antagonist with antiemetic activity. Palonosetron… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
In this study, we investigated the effects of the drugs, palonosetron hydrochloride, bevacizumab and cyclophosphamide, on human… Expand
Is this relevant?
2016
2016
PurposeAntiemetic guidelines recommend co-administration of targeted prophylactic medications inhibiting molecular pathways… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
Review
2015
Review
2015
The prevention of chemotherapy-induced nausea and vomiting (CINV) has been revolutionized over the past 25 years. Guideline-based… Expand
Is this relevant?
2014
2014
BackgroundPostoperative nausea and vomiting (PONV) is one of the most common postsurgical complications. Palonosetron, a 5… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Review
2010
Review
2010
A large number of different 5-hydroxytryptamine (HT)(3) receptor antagonists have been marketed with the indication of preventing… Expand
Is this relevant?
2010
2010
On the strength of two phase III clinical trials, palonosetron hydrochloride was granted FDA approval in March 2008 for the… Expand
  • table 1
  • figure 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
BACKGROUND Palonosetron is a 5-HT(3)-receptor antagonist (5-HT(3)-RA) that has been shown to be superior to other 5-HT(3)-RAs in… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
Is this relevant?
2008
2008
BACKGROUND Emesis and nausea are common adverse effects of chemotherapy. Consequences include dehydration, acute renal failure… Expand
Is this relevant?
2008
2008
Objective:To develop a HPLC method for the test of optical isomers of palonosetron hydrochloride.Methods:The chiral separation… Expand
Is this relevant?
2007
2007
PURPOSE The physical and chemical compatibility of palonosetron hydrochloride with fentanyl citrate, hydromorphone hydrochloride… Expand
Is this relevant?