Palmar-plantar erythrodysesthesia syndrome

Known as: Chemotherapy-Induced Palmoplantar Erythrodysesthesias, Palmoplantar Erythrodysesthesias, Chemotherapy-Induced, Palmoplantar Erythrodysesthesia, Chemotherapy-Induced 
Chemotherapy-induced dermal side effects that are associated with the use of various CYTOSTATIC AGENTS. Symptoms range from mild ERYTHEMA and/or… (More)
National Institutes of Health

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Papers overview

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Highly Cited
2012
Highly Cited
2012
Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study.
BACKGROUND Abiraterone acetate improved overall survival in metastatic castration-resistant prostate cancer at a preplanned… (More)
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Highly Cited
2009
Highly Cited
2009
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma.
PURPOSE A randomized, phase III trial demonstrated superiority of sunitinib over interferon alfa (IFN-alpha) in progression-free… (More)
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Highly Cited
2008
Highly Cited
2008
Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer.
PURPOSE To evaluate whether capecitabine plus oxaliplatin (XELOX) is noninferior to fluorouracil. folinic acid, and oxaliplatin… (More)
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Highly Cited
2007
Highly Cited
2007
Sequential versus combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial
BACKGROUND The optimum use of cytotoxic drugs for advanced colorectal cancer has not been defined. Our aim was to investigate… (More)
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2004
2004
Chemotherapy-induced palmar-plantar erythrodysesthesia syndrome: etiology and emerging therapies.
Palmar-plantar erythrodysesthesia, or hand-foot syndrome (HFS), is emerging as a common, dose-dependent toxicity of many newer… (More)
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Highly Cited
2002
Highly Cited
2002
Superior survival with capecitabine plus docetaxel combination therapy in anthracycline-pretreated patients with advanced breast cancer: phase III trial results.
PURPOSE Docetaxel and capecitabine, a tumor-activated oral fluoropyrimidine, show high single-agent efficacy in metastatic breast… (More)
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Highly Cited
2001
Highly Cited
2001
Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study.
PURPOSE To compare the response rate, efficacy parameters, and toxicity profile of oral capecitabine with bolus intravenous (IV… (More)
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Highly Cited
2001
Highly Cited
2001
Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study.
PURPOSE To compare the efficacy and safety of orally administered capecitabine (Xeloda; Roche Laboratories, Inc, Nutley, NJ), a… (More)
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Review
2000
Review
2000
Antineoplastic therapy-induced palmar plantar erythrodysesthesia ('hand-foot') syndrome. Incidence, recognition and management.
Palmar plantar erythrodysesthesia (PPE) is a distinctive and relatively frequent toxic reaction related to some chemotherapeutic… (More)
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2000
2000
Palmar-plantar erythrodysesthesia syndrome associated with liposomal daunorubicin.
Daunorubicin and doxorubicin are anthracyclines that have efficacy against malignancies such as breast cancer, lung cancer… (More)
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