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Palladium-Bacteriochlorophyll Derivative WST11

Known as: WST11 
National Institutes of Health

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Papers overview

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2019
2019
Medium-term Follow-up of Vascular-targeted Photodynamic Therapy of Localized Prostate Cancer Using TOOKAD Soluble WST-11 (Phase II Trials).
2018
2018
WST11 Vascular Targeted Photodynamic Therapy Effect Monitoring by Multispectral Optoacoustic Tomography (MSOT) in Mice
Objective: Monitoring emerging vascular-targeted photodynamic therapy (VTP) and understanding the time-dynamics of treatment… 
Review
2016
Review
2016
Final Results of a Phase I/II Multicenter Trial of WST11 Vascular Targeted Photodynamic Therapy for Hemi-Ablation of the Prostate in Men with Unilateral Low Risk Prostate Cancer Performed in the…
Highly Cited
2015
Highly Cited
2015
Determination of optimal drug dose and light dose index to achieve minimally invasive focal ablation of localised prostate cancer using WST11‐vascular‐targeted photodynamic (VTP) therapy
To determine the optimal drug and light dose for prostate ablation using WST11 (TOOKAD® Soluble) for vascular‐targeted… 
2011
2011
A model to estimate the outcome of prostate cancer photodynamic therapy with TOOKAD Soluble WST11
Interstitial photodynamic therapy is becoming an interesting modality to treat some early stage prostate cancers. A light… 
2011
2011
Preclinical study of the novel vascular occluding agent, WST11, for photodynamic therapy of the canine prostate.
Highly Cited
2009
Highly Cited
2009
Photocatalytic generation of oxygen radicals by the water-soluble bacteriochlorophyll derivative WST11, noncovalently bound to serum albumin.
Light-induced radical generation is the hallmark of fundamental processes and many applications including photosynthesis and… 
2008
2008
Vascular targeted photodynamic therapy for localized prostate cancer.
Survival for men diagnosed with prostate cancer directly depends on the stage and grade of the disease at diagnosis. Prostate… 
Highly Cited
2005
Highly Cited
2005
WST11, A Novel Water-soluble Bacteriochlorophyll Derivative; Cellular Uptake, Pharmacokinetics, Biodistribution and Vascular-targeted Photodynamic Activity Using Melanoma Tumors as a Model¶
Abstract WST11 is a novel negatively charged water-soluble palladium-bacteriochlorophyll derivative that was developed for… 
2005
2005
Novel Water‐soluble Bacteriochlorophyll Derivatives for Vascular‐targeted Photodynamic Therapy: Synthesis, Solubility, Phototoxicity and the Effect of Serum Proteins ¶
New negatively charged water‐soluble bacteriochlorophyll (Bchl) derivatives were developed in our laboratory for vascular… 
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