PVT1 gene

Known as: LINC00079, NCRNA00079, ONCOGENE PVT1 
This gene plays a role in the activation of transcription.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
PVT1, which maps to chromosome 8q24, is a copy number amplification-associated long non-coding RNA. Overexpression of PVT1 is a… (More)
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Review
2015
Review
2015
It is becoming increasingly clear that short and long noncoding RNAs critically participate in the regulation of cell growth… (More)
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Highly Cited
2015
Highly Cited
2015
Mounting evidence indicates that long noncoding RNAs (lncRNAs) could play a pivotal role in cancer biology. However, the overall… (More)
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Highly Cited
2014
Highly Cited
2014
‘Gain’ of supernumerary copies of the 8q24.21 chromosomal region has been shown to be common in many human cancers and is… (More)
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Highly Cited
2014
Highly Cited
2014
INTRODUCTION Non-small cell lung cancer (NSCLC) is the major cause of cancer death worldwide. Increasing evidence shows that long… (More)
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Highly Cited
2012
Highly Cited
2012
p53 is a tumor suppressor protein that acts as a transcription factor to regulate (either positively or negatively) a plethora of… (More)
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Highly Cited
2011
Highly Cited
2011
Genetic mapping studies have identified multiple cancer susceptibility regions at chromosome 8q24, upstream of the MYC oncogene… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE This study was designed to elucidate the role of amplification at 8q24 in the pathophysiology of ovarian and breast… (More)
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Highly Cited
2007
Highly Cited
2007
To identify genetic variants contributing to end-stage renal disease (ESRD) in type 2 diabetes, we performed a genome-wide… (More)
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Highly Cited
2007
Highly Cited
2007
The functional significance of the Pvt1 locus in the oncogenesis of Burkitt's lymphoma and plasmacytomas has remained a puzzle… (More)
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