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PTX3 protein, human

Known as: TNF Alpha-Induced Protein 5, Pentraxin 3, Pentaxin-Related Protein PTX3 
Pentraxin-related protein PTX3 (381 aa, ~42 kDa) is encoded by the human PTX3 gene. This protein is involved in both inflammation and complement… 
National Institutes of Health

Related topics

Related topics

7 relations
Coiled-Coil DomainExtracellular SpaceLigand BindingPTX3 gene

Broader (1)

PTX3 protein

Papers overview

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Highly Cited
2011
Highly Cited
2011
Prediction of early, intermediate and late pre‐eclampsia from maternal factors, biophysical and biochemical markers at 11–13 weeks
To develop models for prediction of pre‐eclampsia (PE) based on maternal factors and biophysical and biochemical markers at 11–13… 
Highly Cited
2010
Highly Cited
2010
Role of complement and Fc{gamma} receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus.
Pentraxin 3 (PTX3) is a soluble pattern recognition molecule playing a nonredundant role in resistance against Aspergillus… 
Review
2009
Review
2009
Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology
The increasing prevalence of heart failure poses enormous challenges for health care systems worldwide. Despite effective medical… 
Highly Cited
2009
Highly Cited
2009
Associations of Pentraxin 3 With Cardiovascular Disease and All-Cause Death: The Cardiovascular Health Study
Objective—We examined associations of pentraxin 3 (PTX3), a vascular inflammation marker, with incident cardiovascular disease… 
Highly Cited
2008
Highly Cited
2008
Expression of pentraxin 3 (PTX3) in human atherosclerotic lesions
Pentraxin 3 (PTX3) and C‐reactive protein (CRP) are members of the pentraxin superfamily. PTX3 expression is induced in response… 
Highly Cited
2004
Highly Cited
2004
Prognostic Significance of the Long Pentraxin PTX3 in Acute Myocardial Infarction
Background—Inflammation has a pathogenetic role in acute myocardial infarction (MI). Pentraxin-3 (PTX3), a long pentraxin… 
Highly Cited
2004
Highly Cited
2004
Modified atherogenic lipoproteins induce expression of pentraxin-3 by human vascular smooth muscle cells.
Review
2004
Review
2004
Cytokine-induced gene expression at the crossroads of innate immunity, inflammation and fertility: TSG-6 and PTX3/TSG-14.
Highly Cited
2003
Highly Cited
2003
Biochemical and functional characterization of the interaction between pentraxin 3 and C1q
Pentraxin 3 (PTX3) is a recently characterized member of the pentraxin family of acute‐phase proteins produced during… 
Highly Cited
2002
Highly Cited
2002
Increased mortality and inflammation in tumor necrosis factor-stimulated gene-14 transgenic mice after ischemia and reperfusion injury.
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