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PTTG1 protein, human

Known as: hPTTG protein, TUTR1 protein, human, securin, human 
Securin (202 aa, ~22 kDa) is encoded by the human PTTG1 gene. This protein plays a role in chromosomal maintenance.
National Institutes of Health

Related topics

Related topics

8 relations
Cell CycleCell Cycle ControlGenes, RegulatorGenes, cdc

Broader (1)

Securin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Quantitative analyses of the metaphase-to-anaphase transition reveal differential kinetic regulation for securin and cyclin B1.
Separation of sister chromatids is a drastic and irreversible step in the cell cycle. The key biochemistry behind this event is… 
2018
2018
Pituitary tumor-transforming 1 expression in laryngeal cancer and its association with prognosis.
The purpose of the present study was to investigate the association between the expression of pituitary tumor-transforming 1… 
2017
2017
Network analysis of DEGs and verification experiments reveal the notable roles of PTTG1 and MMP9 in lung cancer
Lung cancer, a malignant tumor, is the most frequently fatal cancer, with poor survival rates in the advanced stages. In order to… 
2015
2015
High expression of pituitary tumor-transforming gene-1 predicts poor prognosis in clear cell renal cell carcinoma.
Pituitary tumor-transforming gene-1 (PTTG1) is a recently identified oncogene involved in the progression of malignant tumors… 
2015
2015
Expression of the pituitary tumor transforming gene (PTTG1) in pheochromocytoma as a potential marker for distinguishing benign versus malignant tumors.
The Distinction between malignant and benign pheochromocytoma has always been a diagnostic challenge over the last decades. To… 
2012
2012
RNAi-mediated knockdown of pituitary tumor-transforming gene-1 (PTTG1) suppresses the proliferation and invasive potential of PC3 human prostate cancer cells
Pituitary tumor-transforming gene-1 (PTTG1) is a proto-oncogene that promotes tumorigenesis and metastasis in numerous cell types… 
2008
2008
Pituitary tumor-transforming 1 increases cell motility and promotes lymph node metastasis in esophageal squamous cell carcinoma.
Human pituitary tumor-transforming 1 (PTTG1)/securin is a putative oncoprotein that is overexpressed in various tumor types… 
2006
2006
Mechanisms for growth factor-induced pituitary tumor transforming gene-1 expression in pituitary folliculostellate TtT/GF cells.
PTTG1, a securin protein, also behaves as a transforming gene and is overexpressed in pituitary tumors. Because pituitary… 
2006
2006
Overexpression of pituitary tumor-transforming gene-1 in hepatocellular carcinoma.
BACKGROUND/AIMS Pituitary tumor-transforming gene-1, a recently identified proto-oncogene, was reported to be highly expressed in… 
2003
2003
Over-expression of wild-type Securin leads to aneuploidy in human cells.
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