PTTG1 protein, human

Known as: hPTTG protein, TUTR1 protein, human, securin, human 
Securin (202 aa, ~22 kDa) is encoded by the human PTTG1 gene. This protein plays a role in chromosomal maintenance.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
05101519982018

Papers overview

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2015
2015
Deregulation of the pituitary tumor transforming gene (PTTG1), a newly discovered oncogene, is a hallmark of various malignancies… (More)
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2013
2013
As the most abundant liver-specific microRNA, miR-122 is involved in diverse aspects of hepatic function and neoplastic… (More)
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2009
2009
Cross-resistance to molecules used in endocrine therapy is among the main challenges in the treatment of estrogen receptor-alpha… (More)
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2006
2006
Overexpression of pituitary tumor-transforming 1 (PTTG1) is associated with thyroid cancer. We found elevated PTTG1 levels in the… (More)
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2006
2006
The pituitary tumor transforming (PTTG) gene family comprises PTTG1, 2, and 3. Forced expression of PTTG1 (securin) induces… (More)
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2004
2004
Pituitary tumor transforming gene1 (PTTG1) is a novel oncogene that is expressed in most tumors. It encodes a protein that is… (More)
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Highly Cited
2001
Highly Cited
2001
Abnormalities of chromosome number are the most common genetic aberrations in cancer. The mechanisms regulating the fidelity of… (More)
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2001
2001
We have previously isolated the hpttg proto-oncogene, which is expressed in normal tissues containing proliferating cells and in… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Basic fibroblast growth factor promotes angiogenesis and mitogenesis in colon carcinomas. Pituitary-tumour… (More)
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Highly Cited
1998
Highly Cited
1998
We have isolated a human cDNA clone encoding a novel protein of 22 kDa that is a human counterpart of the rat oncoprotein PTTG… (More)
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