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PTPRT protein, human

Known as: protein tyrosine phosphatase, receptor type, T protein, human, Receptor Type Protein Tyrosine Phosphatase T, PTPRT 
Receptor-type tyrosine-protein phosphatase T (1441 aa, ~162 kDa) is encoded by the human PTPRT gene. This protein is involved in cell-cell adhesion… 
National Institutes of Health

Related topics

Related topics

16 relations
DephosphorylationEnzyme GeneEsterase GeneHydrolase

Broader (1)

Receptor-Like Protein Tyrosine Phosphatases, Class 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
PTPRT epigenetic silencing defines lung cancer with STAT3 activation and can direct STAT3 targeted therapies
ABSTRACT Signal Transducers and Activators of Transcription-3 (STAT3), a potent oncogenic transcription factor, is constitutively… 
2019
2019
miR-532-3p promotes hepatocellular carcinoma progression by targeting PTPRT.
Review
2018
Review
2018
Protein Tyrosine Phosphatases as Potential Regulators of STAT3 Signaling
The signal transducer and activator of transcription 3 (STAT3) protein is a major transcription factor involved in many cellular… 
2016
2016
Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis
Protein tyrosine phosphatase receptor T (PTPRT) is frequently mutated in a variety of human cancers including colorectal cancer… 
Review
2015
Review
2015
Protein tyrosine phosphatase PTPRT as a regulator of synaptic formation and neuronal development
PTPRT/RPTPρ is the most recently isolated member of the type IIB receptor-type protein tyrosine phosphatase family and its… 
2014
2014
PTPRT Regulates High-Fat Diet-Induced Obesity and Insulin Resistance
Obesity is a risk factor for many human diseases. However, the underlying molecular causes of obesity are not well understood… 
2013
2013
PTPRT regulates the interaction of Syntaxin-binding protein 1 with Syntaxin 1 through dephosphorylation of specific tyrosine residue.
Highly Cited
2010
Highly Cited
2010
Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T
Protein tyrosine phosphatase receptor-type T (PTPRT) is the most frequently mutated tyrosine phosphatase in human cancers… 
Highly Cited
2009
Highly Cited
2009
Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn
The receptor‐type protein tyrosine phosphatases (RPTPs) have been linked to signal transduction, cell adhesion, and neurite… 
2008
2008
Tumor-Derived Extracellular Mutations of PTPRT/PTPρ Are Defective in Cell Adhesion
Receptor protein tyrosine phosphatase T (PTPRT/PTPρ) is frequently mutated in human cancers including colon, lung, gastric, and… 
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