PTPNS1 protein, human

Known as: PTPNS1, CD172a protein, human, SHP Substrate-1 
Tyrosine-protein phosphatase non-receptor type substrate 1 (504 aa, ~55 kDa) is encoded by the human SIRPA gene. This protein plays a role in… (More)
National Institutes of Health

Related topics

Related topics

20 relations
Cell AdhesionCell ProliferationImmunoglobulin Family ProteinImmunoglobulin V-set Domain
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Broader (2)

Differentiation AntigensReceptors, Immunologic

Papers overview

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Review
2005
Review
2005
Signal regulatory proteins in the immune system.
Signal regulatory proteins (SIRPs) constitute a family of transmembrane glycoproteins with extracellular Ig-like domains. Several… (More)
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Highly Cited
2004
Highly Cited
2004
Statistical analysis of real clutter at different range resolutions
A statistical analysis is presented of real radar clutter data collected using the McMaster I FIX radar in 1998 and stored in the… (More)
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Highly Cited
2002
Highly Cited
2002
Signal regulatory protein (SIRPalpha), a cellular ligand for CD47, regulates neutrophil transmigration.
Recent studies have demonstrated that CD47 plays an important role in regulating human neutrophil (PMN) chemotaxis. Two ligands… (More)
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Highly Cited
2000
Highly Cited
2000
CD47, a ligand for the macrophage fusion receptor, participates in macrophage multinucleation.
The macrophage fusion receptor (MFR), also called P84/BIT/SIRPalpha/SHPS-1, is a transmembrane glycoprotein that belongs to the… (More)
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Highly Cited
1999
Highly Cited
1999
Integrin-associated protein is a ligand for the P84 neural adhesion molecule.
P84 (also known as SHPS-1, BIT, and SIRP) is a heterophilic adhesive membrane protein involved in receptor tyrosine kinase… (More)
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Highly Cited
1999
Highly Cited
1999
Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47.
Signal-regulatory proteins (SIRPs) comprise a novel transmembrane glycoprotein family involved in the negative regulation of… (More)
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Highly Cited
1998
Highly Cited
1998
Identification of major binding proteins and substrates for the SH2-containing protein tyrosine phosphatase SHP-1 in macrophages.
The protein tyrosine phosphatase SHP-1 is a critical regulator of macrophage biology, but its detailed mechanism of action… (More)
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Highly Cited
1998
Highly Cited
1998
High expression of inhibitory receptor SHPS-1 and its association with protein-tyrosine phosphatase SHP-1 in macrophages.
SHPS-1 (or SIRP) is a member of the immunoglobulin (Ig) superfamily abundantly expressed in neurons and other cell types. Within… (More)
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Highly Cited
1997
Highly Cited
1997
A family of proteins that inhibit signalling through tyrosine kinase receptors
Phosphotyrosine phosphatases are critical negative or positive regulators in the intracellular signalling pathways that result in… (More)
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Highly Cited
1996
Highly Cited
1996
A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion.
Protein tyrosine phosphatases (PTPases), such as SHP-1 and SHP-2, that contain Src homology 2 (SH2) domains play important roles… (More)
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