Skip to search formSkip to main contentSkip to account menu

PTPN7 protein, human

Known as: Tyrosine-Protein Phosphatase Non-Receptor Type 7, HEPTP protein, human, Protein Tyrosine Phosphatase, Non-Receptor Type 7 
Tyrosine-protein phosphatase non-receptor type 7 (360 aa, ~41 kDa) is encoded by the human PTPN7 gene. This protein is involved in the… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Therapeutic inhibition of protein tyrosine phosphatase activity is a compelling yet challenging approach to the treatment of… 
2008
2008
ABSTRACT Stimulation of the β2-adrenergic receptor (β2AR) on a CD40L/interleukin-4-activated B lymphocyte increases the level of… 
Highly Cited
2008
Highly Cited
2008
Previously we reported that when cell cholesterol is acutely lowered with β-methyl-cyclodextrin the amount of activated ERK1/2 in… 
Highly Cited
2006
Highly Cited
2006
Protein tyrosine phosphatases PTPN5, PTPRR and PTPN7 comprise a family of phosphatases that specifically inactivate MAPKs… 
Highly Cited
2005
Highly Cited
2005
T lymphocytes play a central role in controlling adaptive immune responses. IL-2 critically regulates both T cell growth and… 
Highly Cited
2003
Highly Cited
2003
The protein tyrosine phosphatases (PTPs) PTP-SL, STEP and HePTP are mitogen-activated protein kinase (MAPK) substrates and… 
Highly Cited
2003
Highly Cited
2003
The acute depletion of membrane cholesterol causes the concentration of pERK1/2 in caveola/raft lipid domains and the cytosol of… 
Highly Cited
2002
Highly Cited
2002
The extracellular signal-regulated protein kinase 2 (ERK2) is the founding member of a family of mitogen-activated protein… 
Highly Cited
2001
Highly Cited
2001
ABSTRACT The mitogen-activated protein kinases (MAPKs) are signaling molecules that become enzymatically activated through… 
Highly Cited
1994
Highly Cited
1994
Tyrosine phosphorylation is an important regulator of cell growth and differentiation reflecting the interaction of protein…