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PTPN7 protein, human

Known as: Tyrosine-Protein Phosphatase Non-Receptor Type 7, HEPTP protein, human, Protein Tyrosine Phosphatase, Non-Receptor Type 7 
Tyrosine-protein phosphatase non-receptor type 7 (360 aa, ~41 kDa) is encoded by the human PTPN7 gene. This protein is involved in the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Therapeutic inhibition of protein tyrosine phosphatase activity is a compelling yet challenging approach to the treatment of… Expand
Highly Cited
2008
Highly Cited
2008
Previously we reported that when cell cholesterol is acutely lowered with β-methyl-cyclodextrin the amount of activated ERK1/2 in… Expand
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2006
2006
Protein tyrosine phosphatases PTPN5, PTPRR and PTPN7 comprise a family of phosphatases that specifically inactivate MAPKs… Expand
Highly Cited
2005
Highly Cited
2005
T lymphocytes play a central role in controlling adaptive immune responses. IL-2 critically regulates both T cell growth and… Expand
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Highly Cited
2003
Highly Cited
2003
The protein tyrosine phosphatases (PTPs) PTP-SL, STEP and HePTP are mitogen-activated protein kinase (MAPK) substrates and… Expand
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Highly Cited
2003
Highly Cited
2003
The acute depletion of membrane cholesterol causes the concentration of pERK1/2 in caveola/raft lipid domains and the cytosol of… Expand
Highly Cited
2002
Highly Cited
2002
The extracellular signal-regulated protein kinase 2 (ERK2) is the founding member of a family of mitogen-activated protein… Expand
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Highly Cited
2001
Highly Cited
2001
  • Marcela Gronda, Sara Arab, Barbara Iafrate, Haruhiko Suzuki, Brent W. Zanke
  • Molecular and Cellular Biology
  • 2001
  • Corpus ID: 11646223
ABSTRACT The mitogen-activated protein kinases (MAPKs) are signaling molecules that become enzymatically activated through… Expand
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2000
2000
HePTP is a tyrosine specific protein phosphatase that is strongly expressed in activated T-cells. It was recently demonstrated… Expand
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Highly Cited
1994
Highly Cited
1994
Tyrosine phosphorylation is an important regulator of cell growth and differentiation reflecting the interaction of protein… Expand