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PTPN22 protein, human
Known as:
PTPN8 protein, human
, PTPN22
, LyP
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Tyrosine-protein phosphatase non-receptor type 22 (807 aa, ~92 kDa) is encoded by the human PTPN22 gene. This protein is involved in both protein…
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National Institutes of Health
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Related topics
Related topics
21 relations
B-Lymphocytes
Cytoplasm
Dephosphorylation
Enzyme Gene
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Broader (1)
protein-tyrosine phosphatase Lyp
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The PTPN22 R263Q polymorphism confers protection against systemic lupus erythematosus and rheumatoid arthritis, while PTPN22 R620W confers susceptibility to Graves’ disease in a Mexican population
D. López-Cano
,
Daniel Cadena-Sandoval
,
+10 authors
J. Ramírez-Bello
Inflammation Research
2017
Corpus ID: 253599762
The functional PTPN22 R620W polymorphism (rs2476601) is clearly associated with susceptibility to several autoimmune diseases…
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2016
2016
Lack of the Association of the PTPN 22 C 1858 T Gene Polymorphism With Susceptibility to Familial Mediterranean Fever
O. Küçükşahin
,
Z. Şeker
,
+7 authors
A. Ateş
2016
Corpus ID: 33338792
1Department of Internal Medicine, Division of Rheumatology, Medical Faculty of Ankara University, Ankara, Turkey 2Department of…
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2015
2015
Investigating the Association of PTPN22 Gene Polymorphism R620W with Scleroderma in Southwestern Iran in Khuzestan
K. Mowla
,
Elham Rajai
,
Amin Sabbaghan
,
M. Bijan-Zadeh
,
J. Asl
2015
Corpus ID: 54865727
Systemic sclerosis is a chronic systemic disease with unknown variety of etiology, and has clinical chronic protests often…
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2014
2014
Rheumatoid arthritis and psoriasis: Association or coincidence?
N. Akasbi
,
F. Abourazzak
,
T. Harzy
2014
Corpus ID: 74512574
Abstract Introduction Rheumatoid arthritis is a chronic systemic inflammatory disease, which may be associated with other…
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2013
2013
B-cell responses to de novo identified citrullinated fibrinogen peptides are associated with the ptpn22 risk allele
V. Joshua
,
L. Schobers
,
+5 authors
V. Malmström
2013
Corpus ID: 73172934
B-cell responses to de novo identified citrullinated fibrinogen peptides are associated with the PTPN22 risk allele
2012
2012
Evidence of cis-acting regulatory variation in PTPN22 in patients with rheumatoid arthritis
Pille Harrison
,
L. Southam
,
+4 authors
Jennifer J. Pointon
Scandinavian Journal of Rheumatology
2012
Corpus ID: 11723940
Objectives: To assess whether there are cis-regulatory polymorphisms that regulate protein tyrosine phosphatase, non-receptor…
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2012
2012
A PTPN22 promoter polymorphism 21123G>C is associated with RA pathogenesis in Chinese
De-Hua SunJia
2012
Corpus ID: 88959954
The minor allele of the non-synonymous single nucleotide polymorphism (SNP) ?1858C(T within the PTPN22 gene has now been…
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2010
2010
Autoimmune-associated PTPN22 R620W Variation Reduces Phosphorylation of Lymphoid Phosphatase on an Inhibitory
E. Fiorillo
,
V. Orrù
,
+11 authors
Nunzio Bottini
2010
Corpus ID: 263372577
2008
2008
Role of PTPN22 in type 1 diabetes
N. Bottini
2008
Corpus ID: 82789167
A missense single-nucleotide polymorphism, C1858T in the PTPN22 gene, is associated with several human autoimmune diseases…
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2007
2007
T cells: Tuning a T cell's excitation threshold
L. Bird
Nature reviews. Immunology
2007
Corpus ID: 33561966
10.1038/nri2086 How does the same antigenic peptide elicit different responses by T cells that are at different developmental…
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