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PTPN1 protein, human

Known as: Tyrosine-Protein Phosphatase Non-Receptor Type 1, PTP-1B, PTP1B protein, human 
Tyrosine-protein phosphatase non-receptor type 1 (435 aa, ~50 kDa) is encoded by the human PTPN1 gene. This protein plays a role in endocytosis, the… 
National Institutes of Health

Related topics

Related topics

18 relations
CytoplasmDephosphorylationEndoplasmic ReticulumEnzyme Gene

Broader (1)

protein tyrosine phosphatase, non-receptor type 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Abstract A18: microRNA-206 as a potential therapeutic approach for highly-associated NAFLD and HCC
Background and Significance: Non-alcoholic fatty liver disease (NAFLD) is a major risk factor for the development of… 
2014
2014
Candidate Gene SNP Associations With Fat-Free Mass (FFM) Measurements in Horses-In-Training
Introduction Body composition including percentage of fat, fat mass and fat-free mass (FFM) is an important consideration for… 
2014
2014
A2.4 Are protein tyrosine phosphatase-n1 polymorphisms associated with ankylosing spondylitis? – a pilot study
Background and Objectives Association between ankylosing spondylitis (AS) and PTPN1 (protein tyrosine phosphatase, non-receptor… 
2014
2014
Redox and zinc signalling pathways converging on protein tyrosine phosphatases.
2007
2007
Protein tyrosine phosphatase 1B is not a major susceptibility gene for type 2 diabetes mellitus or obesity among Pima Indians
Aim/hypothesisSingle-nucleotide polymorphisms (SNPs) in the protein tyrosine phosphatase 1B gene (PTPN1) have been reported to be… 
2004
2004
Association of the PTPN1 gene with type 2 diabetes and insulin resistance.
Extract: An extensive body of evidence suggests that genes are major contributors to type 2 diabetes (T2DM) susceptibility. Until… 
Review
2002
Review
2002
Regulated Binding of a PTP 1 B-like Phosphatase to N-Cadherin : Control of Cadherin-mediated Adhesion by Dephosphorylation of-Catenin
Cadherins are a family of cell-cell adhesion molecules which play a central role in controlling morphogenetic movements during… 
1999
1999
Pleiotropic effects of zebrafish protein-tyrosine phosphatase-1B on early embryonic development.
Protein tyrosine phosphorylation is an important mechanism of eukaryotic cell signalling which is regulated by protein-tyrosine… 
1999
1999
Role of PTP-1B in aortic smooth muscle cell motility and tyrosine phosphorylation of focal adhesion proteins.
Recent studies have focused attention on the role of protein tyrosine kinases in vascular smooth muscle cell biology, but similar… 
1996
1996
A comparative study of the phosphotyrosyl phosphatase specificity of protein phosphatase type 2A and phosphotyrosyl phosphatase type 1B using phosphopeptides and the phosphoproteins p50/HS1, c-Fgr…
The phosphotyrosyl phosphatase (PTPase) specificity of phosphotyrosyl-phosphatase-activator-(PTPA)-stimulated protein phosphatase… 
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