PTK6 protein, human

Known as: Protein-Tyrosine Kinase 6, Protein-Tyrosine Kinase BRK, protein tyrosine kinase brk, human 
Protein-tyrosine kinase 6 (451 aa, ~52 kDa) is encoded by the human PTK6 gene. This protein is involved in both signal transduction and protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2016
051019862016

Papers overview

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2010
2010
BACKGROUND Proteins that are required for anchorage-independent survival of tumor cells represent attractive targets for… (More)
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2006
2006
BACKGROUND We identified the BRK tyrosine kinase in a PCR-based screen of tyrosine kinases expressed by ovarian tumors. BRK… (More)
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Highly Cited
2005
Highly Cited
2005
The breast tumor kinase (BRK) is a growth promoting non-receptor tyrosine kinase overexpressed in the majority of human breast… (More)
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Highly Cited
2004
Highly Cited
2004
Brk (for breast tumor kinase) is a nonreceptor tyrosine kinase containing SH3, SH2, and tyrosine kinase catalytic domains. Brk… (More)
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2004
2004
Expression of the intracellular tyrosine kinase BRK/Sik is epithelial-specific and regulated during differentiation. Only a few… (More)
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Highly Cited
2003
Highly Cited
2003
Cells normally restrict the nuclear export and expression of intron-containing mRNA. In many cell lines, this restriction can be… (More)
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2001
2001
Signaling by decapentaplegic (Dpp), a Drosophila member of the transforming growth factor (TGF) beta superfamily of growth… (More)
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2000
2000
A high proportion of human breast cancers, in contrast with normal mammary tissue, express the intracellular tyrosine kinase BRK… (More)
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Highly Cited
1997
Highly Cited
1997
BRK is a recently described non receptor protein tyrosine kinase whose mRNA was found to be expressed in human breast tumours and… (More)
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Highly Cited
1996
Highly Cited
1996
To examine the role of BMP signaling during limb pattern formation, we isolated chicken cDNAs encoding type I (BRK-1 and BRK-2… (More)
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