PTEN Phosphohydrolase

Known as: Mutated In Multiple Advanced Cancers 1 Protein, Phosphatase, PTEN, Protein Phosphatase, PTEN 
A lipid phosphatase that contains a C2 DOMAIN and acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS… (More)

Topic mentions per year

Topic mentions per year

2004-2017
012320042017

Papers overview

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2015
2015
BACKGROUND Loss of the tumor suppressor phosphatase and tensin homolog (PTEN) occurs frequently in prostate cancers. Preclinical… (More)
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2015
2015
PTEN is a dual-specificity protein tyrosine phosphatase. As one of the central tumor suppressors, a thorough regulation of its… (More)
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2015
2015
Human cytoplasmic alpha-fetoprotein (AFP) has been classified as a member of the albuminoid gene family. The protein sequence of… (More)
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2014
2014
PTEN dysfunction plays a crucial role in the pathogenesis of hereditary and sporadic cancers. Here, we show that PTEN… (More)
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2013
2013
Intraductal carcinoma of the prostate is a marker of aggressive disease. However, intraductal carcinoma exists on a morphologic… (More)
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2013
2013
Negatively targeting the tumor suppressor and phosphoinositide phosphatase PTEN (phosphatase and tensin homologue) promotes axon… (More)
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2013
2013
Abbreviations GLP1 Glucagon-like peptide-1 GPCR G-protein-coupled receptor MAPK Mitogen-activated protein kinase MTOR Mammalian… (More)
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2011
2011
To detect the expression of miRNA-214 in human gastric cancer cell lines of BGC823, MKN45 and SGC7901, and to identify the effect… (More)
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2011
2011
Purpose: Analytically validated assays to interrogate biomarker status in clinical samples are crucial for personalized medicine… (More)
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2010
2010
BACKGROUND The PTEN phosphatase acts on phosphatidylinositol 3,4,5-triphosphates resulting from phosphatidylinositol 3-kinase… (More)
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