PSMB5 gene

Known as: PSX LARGE MULTIFUNCTIONAL PROTEASE X, LMPX, Proteasome (Prosome, Macropain) Subunit, Beta Type, 5 Gene 
This gene plays a role in proteasome-mediated proteolysis.

Topic mentions per year

Topic mentions per year

1980-2018
051019802018

Papers overview

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2012
2012
Bortezomib (BTZ), a registered proteasome inhibitor (PI) for multiple myeloma, has also been proposed as a potential… (More)
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Highly Cited
2010
Highly Cited
2010
Bortezomib is an effective agent for treating multiple myeloma (MM). To investigate the underlying mechanisms associated with… (More)
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2009
2009
OBJECTIVE To investigate the relationship between bortezomib resistance and mutations in the proteasome beta5 subunit (PSMB5… (More)
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Highly Cited
2008
Highly Cited
2008
The proteasome inhibitor bortezomib is a novel anticancer drug that has shown promise in the treatment of refractory multiple… (More)
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2008
2008
OBJECTIVE To study the mechanism of bortezomib resistance in JurkatB lines derived from T-lymphoblastic lymphoma/leukemia Jurkat… (More)
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2008
2008
To study the mechanism of acquired resistance to bortezomib, a new antitumor drug that is the first therapeutic proteasome… (More)
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2006
2006
The ubiquitin–proteasome system facilitates the degradation of damaged proteins and regulators of growth and stress response… (More)
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2006
2006
The 26S proteasome is responsible for degradation of abnormal intracellular proteins, including oxidatively damaged proteins and… (More)
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2004
2004
The LMP7 and PSMB5 genes were created through an ancient gene duplication event of their ancestral locus. These proteins contain… (More)
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1999
1999
Sequencing of zebrafish (Danio rerio) bacterial artificial chromosome and P1 artificial chromosome genomic clone fragments and of… (More)
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